Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | PHGDH | O43175 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22633972 | 0.76 | MEN1 (0.56) | LMNAL3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL11396585 | 0.73 | CA12 (0.43) | LMNAL3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL5542522 | 0.72 | RAB9A (0.71) | LMNAL3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL22638009 | 0.71 | GAA (0.50) | LMNAL3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL28913363 | 0.71 | ALDH1A1 (0.51) | LMNAL3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL6694830 | 0.70 | LMNA (1.00) | LMNAL3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL1512585 | 0.70 | MEN1 (0.62) | LMNAL3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL11393946 | 0.69 | KMT2A (0.55) | LMNAL3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL11530824 | 0.69 | MEN1 (0.50) | LMNAL3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL3833573 | 0.69 | LMNA (0.68) | LMNAL3MBTL1ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4264502-A | N-(arylthiocarbamoyl)-2-amino-1H-isoindole-1,3-(2H)diones and use as plant growth regulators | GULF OIL CORPORATION (US) | 1981-04-28 | — | — | US | claimed |
| EP-0016571-A1 | N-(Arylthiocarbamoyl)-2-amino-1H-isoindole-1,3-(2H)diones, processes for their preparation and their use as plant growth regulators | Gulf Oil Corporation (US) | 1980-10-01 | — | — | EP | claimed |