Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | LIPE | Q05469 | 1/20 | 0.38 |
| ▸ | SCN7A | Q01118 | 3/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22635853 | 0.86 | L3MBTL1 (0.47) | L3MBTL1HRH3KMT2AHSP90AA1GAA | |
| SCHEMBL17293693 | 0.83 | ALDH1A1 (0.45) | KMT2AGAASMN1; SMN2LMNARAB9A | |
| SCHEMBL30202774 | 0.77 | L3MBTL1 (0.64) | L3MBTL1KMT2AGAASMN1; SMN2LMNA | |
| SCHEMBL2106013 | 0.74 | CYP1A2 (0.53) | — | |
| SCHEMBL29223607 | 0.70 | SMN1; SMN2 (0.45) | L3MBTL1HRH3KMT2AHSP90AA1GAA | |
| SCHEMBL19066133 | 0.68 | ALDH1A1 (0.46) | HRH3KMT2AGAASMN1; SMN2KDM4E | |
| SCHEMBL14001959 | 0.68 | KMT2A (0.56) | L3MBTL1HRH3KMT2AHSP90AA1GAA | |
| SCHEMBL5744624 | 0.68 | NAPRT (0.48) | L3MBTL1LMNARAB9A | |
| SCHEMBL23925146 | 0.68 | L3MBTL1 (0.49) | L3MBTL1KMT2AGAASMN1; SMN2KDM4E | |
| SCHEMBL12331457 | 0.67 | KMT2A (0.51) | L3MBTL1HRH3KMT2AHSP90AA1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020224568-A1 | CDK INHIBITORS | QILU REGOR THERAPEUTICS INC. (CN) | 2020-11-12 | — | — | WO | disclosed |