SCHEMBL22639494

SCHEMBL22639494

c1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(-c4c(-c5ccc(-n6c7ccccc7c7ccccc76)cc5)ccc5ccccc45)cc3)n2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 4/20 0.44
▸ ATM Q13315 3/20 0.44
▸ KDM4E B2RXH2 2/20 0.44
▸ KMT2A Q03164 3/20 0.38
▸ MAPT P10636 3/20 0.35
▸ SMN1; SMN2 Q16637 2/20 0.35
▸ NPC1 O15118 1/20 0.35
▸ LMNA P02545 1/20 0.35
▸ RECQL P46063 1/20 0.35
▸ RAB9A P51151 1/20 0.35
▸ HDAC4 P56524 1/20 0.35
▸ ALOX5 P09917 1/20 0.35
▸ ALDH1A1 P00352 2/20 0.34
▸ MEN1 O00255 2/20 0.34
▸ TSHR P16473 2/20 0.34
▸ TP53 P04637 1/20 0.34
▸ HPGD P15428 1/20 0.34
▸ NFKB1 P19838 1/20 0.34
▸ MAPK1 P28482 1/20 0.34
▸ NFKB2 Q00653 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22639426 0.99 ATM (0.42) L3MBTL1ATMKDM4EKMT2AMAPT
SCHEMBL23319005 0.95 L3MBTL1 (0.44) L3MBTL1ATMKDM4EKMT2AMAPT
SCHEMBL22639431 0.93 KDM4E (0.38) L3MBTL1ATMKDM4EKMT2AMAPT
SCHEMBL22639390 0.93 KDM4E (0.40) L3MBTL1ATMKDM4EKMT2AMAPT
SCHEMBL22639382 0.92 ATM (0.39) L3MBTL1ATMKDM4EKMT2AMAPT
SCHEMBL25679966 0.91 ATM (0.41) L3MBTL1ATMKDM4EKMT2AMAPT
SCHEMBL22639425 0.91 KDM4E (0.38) L3MBTL1ATMKDM4EKMT2AMAPT
SCHEMBL24787784 0.89 KDM4E (0.39) L3MBTL1ATMKDM4EKMT2AMAPT
SCHEMBL24824200 0.89 KDM4E (0.36) L3MBTL1ATMKDM4EKMT2AMAPT
SCHEMBL20405005 0.88 KDM4E (0.38) L3MBTL1ATMKDM4EKMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220416171-A1 ORGANIC ELECTROLUMINESCENT DEVICE CONFIGURED TO EMIT LIGHT WITH HIGH LUMINOUS EFFICIENCY IDEMITSU KOSAN CO.,LTD. (JP) 2022-12-29 — — US disclosed
US-20220173334-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS EQUIPPED WITH THE SAME IDEMITSU KOSAN CO.,LTD. (JP) 2022-06-02 — — US disclosed
US-20220165964-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS PROVIDED WITH THE SAME IDEMITSU KOSAN CO.,LTD. (JP) 2022-05-26 — — US disclosed
EP-3372593-B1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME LG CHEMICAL LTD (KR) 2020-12-23 — — EP disclosed
US-10833278-B2 Compound and organic light emitting device comprising the same LG CHEM, LTD. (KR) 2020-11-10 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10833278-B2 Compound and organic light emitting device comprising the same CRY1, CRY2, ORC3 L3MBTL1 1353/4885ATM 2733/4885KDM4E 2260/4885
US-20220165964-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS PROVIDED WITH THE SAME LEF1, OR10J3, RER1 L3MBTL1 691/4885ATM 3029/4885KDM4E 2867/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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