SCHEMBL22648008

SCHEMBL22648008

C=C(C)C(=O)OCCNC(=O)OCCOC(C)C

nearest known ligand 0.44

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.44
TSHR P16473 3/20 0.42
ACHE P22303 7/20 0.41
CHRNB2 P17787 2/20 0.37
CHRNB4 P30926 2/20 0.37
CHRNA3 P32297 2/20 0.37
CHRNA4 P43681 2/20 0.37
SMN1; SMN2 Q16637 1/20 0.36
ALDH1A1 P00352 1/20 0.36
LMNA P02545 1/20 0.35
HTT P42858 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26345433 0.91 TSHR (0.47) TSHRACHEALDH1A1HTT
SCHEMBL2403793 0.89 THRB (0.53) THRBTSHRACHEALDH1A1
SCHEMBL13872030 0.89 THRB (0.53) THRBTSHRACHEALDH1A1
SCHEMBL15233348 0.89 THRB (0.46) THRBTSHRACHECHRNB2CHRNB4
SCHEMBL22652991 0.88 THRB (0.41) THRBTSHRACHECHRNB2CHRNB4
SCHEMBL11920458 0.87 THRB (0.44) THRBTSHRACHECHRNB2CHRNB4
SCHEMBL13478195 0.86 THRB (0.45) THRBTSHRACHECHRNB2CHRNB4
SCHEMBL554732 0.85 THRB (0.57) THRBTSHRSMN1; SMN2ALDH1A1HTT
SCHEMBL12746641 0.85 THRB (0.44) THRBTSHRACHECHRNB2CHRNB4
SCHEMBL18329111 0.85 THRB (0.45) THRBTSHRACHECHRNB2CHRNB4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11780819-B2 Aromatic substituted alkane-core monomers and polymers thereof for volume Bragg gratings META PLATFORMS TECHNOLOGIES, LLC (US) 2023-10-10 US disclosed
US-11718580-B2 Fluorene derivatized monomers and polymers for volume Bragg gratings META PLATFORMS TECHNOLOGIES, LLC (US) 2023-08-08 US disclosed
US-11543584-B2 Inorganic matrix nanoimprint lithographs and methods of making thereof with reduced carbon META PLATFORMS TECHNOLOGIES, LLC (US) 2023-01-03 US disclosed
WO-2022147180-A1 HIGH REFRACTIVE INDEX OVERCOAT FORMULATION AND METHOD OF USE WITH INKJET PRINTING META PLATFORMS TECHNOLOGIES, LLC (US) 2022-07-07 WO disclosed
US-20220204790-A1 HIGH REFRACTIVE INDEX OVERCOAT FORMULATION AND METHOD OF USE WITH INKJET PRINTING META PLATFORMS TECHNOLOGIES, LLC 2022-06-30 US disclosed
US-20220153895-A1 SUBSTITUTED PROPANE-CORE MONOMERS AND POLYMERS THEREOF FOR VOLUME BRAGG GRATINGS META PLATFORMS TECHNOLOGIES, LLC 2022-05-19 US disclosed
WO-2022104137-A1 SUBSTITUTED PROPANE-CORE MONOMERS AND POLYMERS THEREOF FOR VOLUME BRAGG GRATINGS FACEBOOK TECHNOLOGIES, LLC (US) 2022-05-19 WO disclosed
US-20220019015-A1 INORGANIC MATRIX NANOIMPRINT LITHOGRAPHS AND METHODS OF MAKING THEREOF META PLATFORMS TECHNOLOGIES, LLC 2022-01-20 US disclosed
WO-2021108232-A1 ANTHRAQUINONE DERIVATIZED MONOMERS AND POLYMERS FOR VOLUME BRAGG GRATINGS FACEBOOK TECHNOLOGIES, LLC (US) 2021-06-03 WO disclosed
WO-2021108597-A1 THIOPHOSPHATE AND PHOSPHINE SULFIDE DERIVATIZED MONOMERS AND POLYMERS FOR VOLUME BRAGG GRATINGS FACEBOOK TECHNOLOGIES, LLC (US) 2021-06-03 WO disclosed
WO-2021108282-A1 AROMATIC SUBSTITUTED METHANE-CORE MONOMERS AND POLYMERS THEREOF FOR VOLUME BRAGG GRATINGS FACEBOOK TECHNOLOGIES, LLC (US) 2021-06-03 WO disclosed
US-20210155599-A1 AROMATIC SUBSTITUTED ALKANE-CORE MONOMERS AND POLYMERS THEREOF FOR VOLUME BRAGG GRATINGS META PLATFORMS TECHNOLOGIES, LLC 2021-05-27 US disclosed
US-20210155584-A1 AROMATIC SUBSTITUTED METHANE-CORE MONOMERS AND POLYMERS THEREOF FOR VOLUME BRAGG GRATINGS META PLATFORMS TECHNOLOGIES, LLC 2021-05-27 US disclosed
US-20210155585-A1 ANTHRAQUINONE DERIVATIZED MONOMERS AND POLYMERS FOR VOLUME BRAGG GRATINGS META PLATFORMS TECHNOLOGIES, LLC 2021-05-27 US disclosed
US-20200354311-A1 FLUORENE DERIVATIZED MONOMERS AND POLYMERS FOR VOLUME BRAGG GRATINGS META PLATFORMS TECHNOLOGIES, LLC 2020-11-12 US disclosed
US-20200355997-A1 THIANTHRENE DERIVATIZED MONOMERS AND POLYMERS FOR VOLUME BRAGG GRATINGS META PLATFORMS TECHNOLOGIES, LLC 2020-11-12 US disclosed
WO-2020227276-A1 THIANTHRENE DERIVATIZED MONOMERS AND POLYMERS FOR VOLUME BRAGG GRATINGS FACEBOOK TECHNOLOGIES, LLC (US) 2020-11-12 WO disclosed
WO-2020227264-A1 FLUORENE DERIVATIZED MONOMERS AND POLYMERS FOR VOLUME BRAGG GRATINGS FACEBOOK TECHNOLOGIES, LLC (US) 2020-11-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210155585-A1 ANTHRAQUINONE DERIVATIZED MONOMERS AND POLYMERS FOR VOLUME BRAGG GRATINGS BLM, AAAS, RECQL THRB 4884/4885TSHR 4811/4885ACHE 488/4885
US-20200355997-A1 THIANTHRENE DERIVATIZED MONOMERS AND POLYMERS FOR VOLUME BRAGG GRATINGS TST, SMO, BRAP THRB 2918/4885TSHR 1694/4885ACHE 781/4885
US-20200354311-A1 FLUORENE DERIVATIZED MONOMERS AND POLYMERS FOR VOLUME BRAGG GRATINGS RHOA, PARG, LSG1 THRB 4265/4885TSHR 3624/4885ACHE 994/4885
US-11718580-B2 Fluorene derivatized monomers and polymers for volume Bragg gratings RHOA, PARG, LSG1 THRB 4265/4885TSHR 3624/4885ACHE 994/4885
US-20210155584-A1 AROMATIC SUBSTITUTED METHANE-CORE MONOMERS AND POLYMERS THEREOF FOR VOLUME BRAGG GRATINGS SMAD2, MAFG, MYO1G THRB 4727/4885TSHR 4798/4885ACHE 168/4885
US-20210155599-A1 AROMATIC SUBSTITUTED ALKANE-CORE MONOMERS AND POLYMERS THEREOF FOR VOLUME BRAGG GRATINGS SMAD2, ALK, SMAD3 THRB 4283/4885TSHR 4511/4885ACHE 272/4885
US-11780819-B2 Aromatic substituted alkane-core monomers and polymers thereof for volume Bragg gratings SMAD2, ALK, SMAD3 THRB 4283/4885TSHR 4511/4885ACHE 272/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.