Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.41 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.40 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.40 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 7/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1662799 | 0.86 | NR1H2 (0.41) | NR1H2MAPTALDH1A1LMNAPDE4B | |
| SCHEMBL31487442 | 0.84 | MAPT (0.51) | NR1H2MAPTALDH1A1LMNASMARCA2 | |
| SCHEMBL21245582 | 0.84 | MAPT (0.51) | NR1H2MAPTALDH1A1LMNASMARCA2 | |
| SCHEMBL22650493 | 0.82 | NR1H2 (0.54) | NR1H2PDE4BPDE7AESR2P2RX7 | |
| SCHEMBL29507776 | 0.82 | NR1H2 (0.54) | NR1H2PDE4BPDE7AESR2P2RX7 | |
| SCHEMBL4537183 | 0.81 | P2RX7 (0.55) | P2RX7 | |
| SCHEMBL1583488 | 0.81 | MEN1 (0.51) | NR1H2MAPTP2RX7MAPK1KDM4E | |
| SCHEMBL30734152 | 0.81 | MEN1 (0.51) | NR1H2MAPTP2RX7MAPK1KDM4E | |
| SCHEMBL22650491 | 0.80 | NR1H2 (0.46) | NR1H2MAPTALDH1A1LMNASMARCA2 | |
| SCHEMBL1662960 | 0.80 | P2RX7 (0.44) | NR1H2MAPTLMNAPDE4BPDE7A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020224568-A1 | CDK INHIBITORS | QILU REGOR THERAPEUTICS INC. (CN) | 2020-11-12 | — | — | WO | disclosed |