Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 2/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.41 |
| ▸ | RBP4 | P02753 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.40 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 2/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | STS | P08842 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | F13A1 | P00488 | 1/20 | 0.38 |
| ▸ | TGM2 | P21980 | 1/20 | 0.38 |
| ▸ | TGM1 | P22735 | 1/20 | 0.38 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22650385 | 0.86 | NR1H2 (0.44) | NR1H2P2RX7PDE4BPDE7AMAPT | |
| SCHEMBL1663317 | 0.82 | NR1H2 (0.40) | NR1H2P2RX7RBP4PDE4BPDE7A | |
| SCHEMBL1662800 | 0.81 | PTGDR2 (0.44) | P2RX7RBP4MAPTALDH1A1LMNA | |
| SCHEMBL1584703 | 0.81 | CPS1 (0.46) | NR1H2P2RX7MAPTKDM4EALDH1A1 | |
| SCHEMBL1663275 | 0.81 | GALR2 (0.43) | NR1H2PDE4BMAPTKDM4EPDE4A | |
| SCHEMBL4537183 | 0.79 | P2RX7 (0.55) | P2RX7MKNK1 | |
| SCHEMBL1583488 | 0.79 | MEN1 (0.51) | NR1H2P2RX7MAPTKDM4EMAPK1 | |
| SCHEMBL30734152 | 0.79 | MEN1 (0.51) | NR1H2P2RX7MAPTKDM4EMAPK1 | |
| SCHEMBL1662960 | 0.78 | P2RX7 (0.44) | NR1H2P2RX7PDE4BPDE7AMAPT | |
| SCHEMBL22650493 | 0.78 | NR1H2 (0.54) | NR1H2P2RX7PDE4BPDE7AESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011050284-A1 | PYRAZOLYLPYRIDINE ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2011-04-28 | — | — | WO | disclosed |