Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | TDP2 | O95551 | 1/20 | 0.47 |
| ▸ | NSD2 | O96028 | 1/20 | 0.47 |
| ▸ | HK1 | P19367 | 1/20 | 0.47 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.47 |
| ▸ | PARG | Q86W56 | 6/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31121547 | 1.00 | PKM (0.47) | PKMSMN1; SMN2KMT2AMAPK1MEN1 | |
| SCHEMBL55616 | 1.00 | PKM (0.47) | PKMSMN1; SMN2KMT2AMAPK1MEN1 | |
| SCHEMBL2264974 | 0.95 | PKM (0.48) | PKMSMN1; SMN2KMT2AMAPK1MEN1 | |
| SCHEMBL30007977 | 0.94 | KMT2A (0.56) | PKMSMN1; SMN2KMT2AMAPK1MEN1 | |
| SCHEMBL919135 | 0.94 | KMT2A (0.56) | PKMSMN1; SMN2KMT2AMAPK1MEN1 | |
| SCHEMBL21104695 | 0.92 | SMN1; SMN2 (0.54) | PKMSMN1; SMN2KMT2AMAPK1MEN1 | |
| SCHEMBL10070529 | 0.90 | PARG (0.44) | PKMSMN1; SMN2KMT2AMAPK1MEN1 | |
| SCHEMBL25171455 | 0.89 | TDP2 (0.56) | PKMSMN1; SMN2KMT2AMAPK1MEN1 | |
| Dioxane SCHEMBL28440846 | 0.84 | PARG (0.49) | PKMSMN1; SMN2KMT2AMAPK1MEN1 | |
| SCHEMBL11856834 | 0.81 | SMN1; SMN2 (0.46) | PKMSMN1; SMN2KMT2AMAPK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3543209-A1 | PROCESS FOR MANUFACTURING AN AQUEOUS HYDROGEN PEROXIDE SOLUTION | SOLVAY SA (BE) | 2019-09-25 | — | — | EP | disclosed |
| US-8445440-B2 | Dimeric IAP inhibitors | NOVARTIS AG (CH) | 2013-05-21 | — | — | US | disclosed |
| EP-2539333-A1 | DIMERIC IAP INHIBITORS | Novartis AG (CH) | 2013-01-02 | — | — | EP | disclosed |
| WO-2011104266-A1 | DIMERIC IAP INHIBITORS | NOVARTIS AG (CH) | 2011-09-01 | — | — | WO | disclosed |
| US-20110206690-A1 | DIMERIC IAP INHIBITORS | NOVARTIS AG (CH) | 2011-08-25 | — | — | US | disclosed |
| US-20100222454-A1 | DEGRADATION ACCELERATOR FOR POLYMERS AND POLYMER ARTICLE COMPRISING IT | CIBA CORPORATION (US) | 2010-09-02 | — | — | US | disclosed |
| US-20100222454-A1 | DEGRADATION ACCELERATOR FOR POLYMERS AND POLYMER ARTICLE COMPRISING IT | CIBA CORPORATION (US) | 2010-09-02 | — | — | US | disclosed |
| WO-2009016083-A1 | DEGRADATION ACCELERATOR FOR POLYMERS AND POLYMER ARTICLE COMPRISING IT | BASF SE (CH) | 2009-02-05 | — | — | WO | disclosed |
| EP-1377536-A4 | SELF-REDUCING ANTHRAQUINONE COMPOUNDS | COMMW SCIENT AND RES ORGANISAT (AU) | 2007-02-28 | — | — | EP | disclosed |
| EP-1351948-A4 | NEW OXYGEN SCAVENGING COMPOSITIONS | COMMW SCIENT IND RES ORG (AU) | 2005-06-29 | — | — | EP | disclosed |
| EP-0833626-A1 | MONO- AND DISULFO-SUBSTITUTED ANTHRAQUINONES AND THEIR USE FOR THE TREATMENT OF BONE MATRIX DISORDERS | Boonville Limited (VG) | 1998-04-08 | — | — | EP | disclosed |
| WO-1997000675-A1 | MONO- AND DISULFO-SUBSTITUTED ANTHRAQUINONES AND THEIR USE FOR THE TREATMENT OF BONE MATRIX DISORDERS | BOONVILLE LIMITED (VG) | 1997-01-09 | — | — | WO | disclosed |
| EP-0673348-A1 | PRODUCTION OF HYDROGEN PEROXIDE | GUILLET, James Edwin (CA) | 1995-09-27 | — | — | EP | disclosed |
| WO-1995010480-A1 | PRODUCTION OF HYDROGEN PEROXIDE | GUILLET JAMES E (CA) | 1995-04-20 | — | — | WO | disclosed |
| EP-0024746-B1 | PROCESS FOR THE ABSORPTION AND REMOVAL OF HYDROGEN SULPHIDE AS ELEMENTAL SULPHUR FROM GASES OR GAS MIXTURES, AND AN ALKALINE SOLUTION CONTAINING A DERIVATIVE OF ANTHRAQUINONE SULFONIC ACID AMIDE | CIBA-GEIGY AG (CH) | 1983-03-02 | — | — | EP | disclosed |
| EP-0008641-B1 | ANTHRAQUINONESULPHONAMIDES AND PROCESS FOR THEIR MANUFACTURE | CIBA-GEIGY AG (CH) | 1982-01-13 | — | — | EP | disclosed |
| US-4276224-A | Anthraquinone sulphonamide compounds and preparation | CIBA-GEIGY CORPORATION (US) | 1981-06-30 | — | — | US | disclosed |
| EP-0024746-A1 | Process for the absorption and removal of hydrogen sulphide as elemental sulphur from gases or gas mixtures, and an alkaline solution containing a derivative of anthraquinone sulfonic acid amide | CIBA-GEIGY AG (CH) | 1981-03-11 | — | — | EP | disclosed |
| EP-0008641-A1 | Anthraquinonesulphonamides and process for their manufacture | CIBA-GEIGY AG (CH) | 1980-03-19 | — | — | EP | disclosed |
| US-3983248-A | VIRICIDES | RICHARDSON-MERRELL INC. (US) | 1976-09-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110206690-A1 | DIMERIC IAP INHIBITORS | XIAP, BIRC5, BIRC2 | PKM 2733/4885SMN1; SMN2 1010/4885KMT2A 3756/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.