SCHEMBL30007977

SCHEMBL30007977

O=C1c2ccccc2C(=O)c2cc(S(=O)(=O)Cl)ccc21

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.56
MEN1 O00255 4/20 0.56
SMN1; SMN2 Q16637 3/20 0.56
MAPK1 P28482 3/20 0.56
MAPT P10636 3/20 0.56
HTT P42858 2/20 0.56
PKM P14618 1/20 0.56
PARG Q86W56 7/20 0.54
TDP1 Q9NUW8 3/20 0.50
ALDH1A1 P00352 2/20 0.50
ELANE P08246 1/20 0.50
STAT3 P40763 1/20 0.50
CDC25B P30305 1/20 0.50
NPC1 O15118 1/20 0.50
TP53 P04637 1/20 0.50
CYP3A4 P08684 1/20 0.50
TSHR P16473 1/20 0.50
RAB9A P51151 1/20 0.50
S100A4 P26447 1/20 0.48
BCL2 P10415 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL919135 1.00 KMT2A (0.56) KMT2AMEN1SMN1; SMN2MAPK1MAPT
SCHEMBL21104695 0.98 SMN1; SMN2 (0.54) KMT2AMEN1SMN1; SMN2MAPK1MAPT
SCHEMBL55616 0.94 PKM (0.47) KMT2AMEN1SMN1; SMN2MAPK1MAPT
SCHEMBL2265043 0.94 PKM (0.47) KMT2AMEN1SMN1; SMN2MAPK1MAPT
SCHEMBL31121547 0.94 PKM (0.47) KMT2AMEN1SMN1; SMN2MAPK1MAPT
Dioxane SCHEMBL28440846 0.89 PARG (0.49) KMT2AMEN1SMN1; SMN2MAPK1MAPT
SCHEMBL2264974 0.89 PKM (0.48) KMT2AMEN1SMN1; SMN2MAPK1MAPT
Tetrahydrofuran SCHEMBL28451095 0.87 PARG (0.47) KMT2AMEN1SMN1; SMN2MAPK1MAPT
SCHEMBL10070529 0.84 PARG (0.44) KMT2AMEN1SMN1; SMN2MAPK1MAPT
SCHEMBL25171455 0.83 TDP2 (0.56) KMT2AMEN1SMN1; SMN2MAPK1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117769438-A Derivatized or rapidly polymerizable collagen compositions for tissue augmentation comprising non-absorbable or slowly absorbable polymers 上海其胜生物制剂有限公司 2024-03-26 CN disclosed
EP-4337258-A1 DERIVATIZED OR RAPIDLY POLYMERIZING COLLAGEN COMPOSITIONS FOR TISSUE AUGMENTATION CONTAINING NON-RESORBABLE OR SLOWLY RESORBABLE POLYMERS Shanghai Qisheng Biological Preparation Co., Ltd. (CN) 2024-03-20 EP disclosed
WO-2022237900-A1 DERIVATIZED OR RAPIDLY POLYMERIZING COLLAGEN COMPOSITIONS FOR TISSUE AUGMENTATION CONTAINING NON-RESORBABLE OR SLOWLY RESORBABLE POLYMERS SHANGHAI QISHENG BIOLOGICAL PREPARATION CO., LTD. (CN) 2022-11-17 WO disclosed