Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 4/20 | 0.51 |
| ▸ | CCND1 | P24385 | 4/20 | 0.51 |
| ▸ | CDK6 | Q00534 | 2/20 | 0.51 |
| ▸ | BMPR2 | Q13873 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 4/20 | 0.35 |
| ▸ | RPS6KA6 | Q9UK32 | 2/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | FYN | P06241 | 1/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.34 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.34 |
| ▸ | PRKACA | P17612 | 1/20 | 0.34 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.34 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.34 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.34 |
| ▸ | PRKACG | P22612 | 1/20 | 0.34 |
| ▸ | PRKACB | P22694 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22650754 | 0.91 | CDK4 (0.51) | CDK4CCND1CDK6BMPR2NPC1 | |
| SCHEMBL22650761 | 0.90 | CDK4 (0.51) | CDK4CCND1CDK6BMPR2NPC1 | |
| SCHEMBL22650552 | 0.85 | CDK4 (0.53) | CDK4CCND1CDK6BMPR2NPC1 | |
| SCHEMBL22650757 | 0.85 | CDK4 (0.35) | CDK4CCND1CDK6CDK2CCNT1 | |
| SCHEMBL22650556 | 0.82 | CDK4 (0.52) | CDK4CCND1CDK6BMPR2NPC1 | |
| SCHEMBL22650551 | 0.81 | CDK6 (0.52) | CDK4CCND1CDK6NPC1RAB9A | |
| SCHEMBL22650544 | 0.77 | CDK4 (0.56) | CDK4CCND1CDK6BMPR2NPC1 | |
| SCHEMBL22650545 | 0.75 | CDK4 (0.55) | CDK4CCND1CDK6BMPR2NPC1 | |
| SCHEMBL22650762 | 0.73 | CDK6 (0.67) | CDK4CCND1CDK6CDK2CCNT1 | |
| SCHEMBL22650749 | 0.69 | CDK4 (0.54) | CDK4CCND1CDK6SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020224568-A1 | CDK INHIBITORS | QILU REGOR THERAPEUTICS INC. (CN) | 2020-11-12 | — | — | WO | disclosed |