Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 9/20 | 0.37 |
| ▸ | MTOR | P42345 | 8/20 | 0.37 |
| ▸ | PIK3R1 | P27986 | 6/20 | 0.37 |
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | RICTOR | Q6R327 | 5/20 | 0.36 |
| ▸ | RPTOR | Q8N122 | 5/20 | 0.36 |
| ▸ | MAPKAP1 | Q9BPZ7 | 5/20 | 0.36 |
| ▸ | MLST8 | Q9BVC4 | 5/20 | 0.36 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.35 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.35 |
| ▸ | FEN1 | P39748 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22650819 | 0.88 | HRH3 (0.39) | HRH3L3MBTL3L3MBTL1HRH1 | |
| SCHEMBL22650822 | 0.82 | CHRNB2 (0.37) | HRH3HRH1 | |
| SCHEMBL22650820 | 0.81 | CHRNB2 (0.34) | HRH3L3MBTL3ALOX5APFEN1HRH1 | |
| SCHEMBL29437377 | 0.80 | L3MBTL3 (0.50) | PIK3CAMTORPIK3R1AKT1ACVR1 | |
| SCHEMBL2723240 | 0.80 | L3MBTL3 (0.50) | PIK3CAMTORPIK3R1AKT1ACVR1 | |
| SCHEMBL12280261 | 0.77 | PIK3CA (0.43) | PIK3CAMTORPIK3R1AKT1TDP1 | |
| SCHEMBL22650564 | 0.77 | HRH3 (0.44) | TSHRHRH3L3MBTL1ALDH1A1MAPK1 | |
| SCHEMBL22650730 | 0.76 | ALOX5AP (0.40) | PIK3CAMTORHRH3ALDH1A1ALOX5AP | |
| SCHEMBL29462406 | 0.76 | F10 (0.49) | PIK3CAMTORPIK3R1 | |
| SCHEMBL2343226 | 0.76 | F10 (0.49) | PIK3CAMTORPIK3R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020224568-A1 | CDK INHIBITORS | QILU REGOR THERAPEUTICS INC. (CN) | 2020-11-12 | — | — | WO | disclosed |