Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRR1 | P24046 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.37 |
| ▸ | HTR3B | O95264 | 1/20 | 0.37 |
| ▸ | HTR3A | P46098 | 1/20 | 0.37 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.37 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.36 |
| ▸ | FDPS | P14324 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HRH2 | P25021 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2114938 | 0.74 | KDM4E (0.63) | KDM4ELMNASMN1; SMN2HSD17B10RAB9A | |
| SCHEMBL22656785 | 0.74 | KDM4E (0.42) | GABRR1KDM4ELMNASMN1; SMN2HSD17B10 | |
| SCHEMBL266474 | 0.74 | — | — | |
| SCHEMBL2588734 | 0.72 | — | — | |
| Hydrochloric Acid SCHEMBL3448931 | 0.72 | KDM4E (0.51) | GABRR1KDM4ESMN1; SMN2HSD17B10CYP2C19 | |
| SCHEMBL11619128 | 0.71 | GABRR1 (0.39) | GABRR1KDM4ESMN1; SMN2HSD17B10CYP2C19 | |
| SCHEMBL11725688 | 0.71 | LMNA (0.73) | KDM4ELMNASMN1; SMN2HSD17B10CYP2C19 | |
| Potassium Ion SCHEMBL11400680 | 0.71 | GABRR1 (0.44) | GABRR1KDM4ELMNASMN1; SMN2HSD17B10 | |
| Hydrochloric Acid SCHEMBL11004255 | 0.71 | GABRR1 (0.44) | GABRR1KDM4ELMNASMN1; SMN2HSD17B10 | |
| SCHEMBL11395637 | 0.71 | GABRR1 (0.44) | GABRR1KDM4ELMNASMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3747881-B1 | NITROGEN-CONTAINING BENZOHETEROCYCLE COMPOUND COMPRISING CARBOXYLIC ACID GROUP, PREPARATION METHOD AND USE THEREOF | SICHUAN KELUN BIOTECH BIOPHARMACEUTICAL CO LTD (CN) | 2023-08-23 | — | — | EP | disclosed |
| US-11292785-B2 | Nitrogen-containing benzoheterocycle compound comprising carboxylic acid group, preparation method and use thereof | SICHUAN KELUN-BIOTECH BIOPHARMACEUTICAL CO., LTD. (CN) | 2022-04-05 | — | — | US | disclosed |
| EP-3747881-A1 | NITROGEN-CONTAINING BENZOHETEROCYCLE COMPOUND COMPRISING CARBOXYLIC ACID GROUP, PREPARATION METHOD AND USE THEREOF | Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. (CN) | 2020-12-09 | — | — | EP | disclosed |
| US-20200361911-A1 | NITROGEN-CONTAINING BENZOHETEROCYCLE COMPOUND COMPRISING CARBOXYLIC ACID GROUP, PREPARATION METHOD AND USE THEREOF | SICHUAN KELUN-BIOTECH BIOPHARMACEUTICAL CO., LTD. (CN) | 2020-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200361911-A1 | NITROGEN-CONTAINING BENZOHETEROCYCLE COMPOUND COMPRISING CARBOXYLIC ACID GROUP, PREPARATION METHOD AND USE THEREOF | CCR2, CCR5, CCR1 | GABRR1 567/4885KDM4E 3329/4885LMNA 2717/4885 |
| US-11292785-B2 | Nitrogen-containing benzoheterocycle compound comprising carboxylic acid group, preparation method and use thereof | CCR2, CCR5, CCR1 | GABRR1 567/4885KDM4E 3329/4885LMNA 2717/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.