Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 4/20 | 0.44 |
| ▸ | MAOB | P27338 | 4/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 5/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 4/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30207384 | 0.88 | ADRB2 (0.52) | MAOAMAOBKDM1ANPC1RAB9A | |
| SCHEMBL22657360 | 0.88 | ADRB2 (0.52) | MAOAMAOBKDM1ANPC1RAB9A | |
| SCHEMBL22657362 | 0.88 | ADRB2 (0.52) | MAOAMAOBKDM1ANPC1RAB9A | |
| SCHEMBL22657361 | 0.88 | ADRB2 (0.52) | MAOAMAOBKDM1ANPC1RAB9A | |
| SCHEMBL21092394 | 0.87 | MAOA (0.46) | MAOAMAOBKDM1ANPC1RAB9A | |
| SCHEMBL22657345 | 0.87 | MAOA (0.46) | MAOAMAOBKDM1ANPC1RAB9A | |
| SCHEMBL21054853 | 0.87 | MAOA (0.46) | MAOAMAOBKDM1ANPC1RAB9A | |
| SCHEMBL21054854 | 0.87 | MAOA (0.46) | MAOAMAOBKDM1ANPC1RAB9A | |
| SCHEMBL21092393 | 0.87 | MAOA (0.46) | MAOAMAOBKDM1ANPC1RAB9A | |
| SCHEMBL21053143 | 0.87 | MAOA (0.46) | MAOAMAOBKDM1ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11590089-B2 | Beta-2 selective adrenergic receptor agonists | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2023-02-28 | — | — | US | disclosed |
| US-20200360304-A1 | BETA-2 SELECTIVE ADRENERGIC RECEPTOR AGONISTS | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2020-11-19 | — | — | US | disclosed |
| US-20200360304-A1 | BETA-2 SELECTIVE ADRENERGIC RECEPTOR AGONISTS | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2020-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11590089-B2 | Beta-2 selective adrenergic receptor agonists | ADRB2, ADRB1, ADRA2C | MAOA 1468/4885MAOB 1029/4885KDM1A 4832/4885 |
| US-20200360304-A1 | BETA-2 SELECTIVE ADRENERGIC RECEPTOR AGONISTS | ADRB2, ADRB1, ADRA2C | MAOA 1468/4885MAOB 1029/4885KDM1A 4832/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.