Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 4/20 | 0.46 |
| ▸ | MAOB | P27338 | 4/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 3/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21054854 | 1.00 | MAOA (0.46) | MAOAMAOBDRD2KDM1ANPC1 | |
| SCHEMBL21092393 | 1.00 | MAOA (0.46) | MAOAMAOBDRD2KDM1ANPC1 | |
| SCHEMBL22657376 | 1.00 | MAOA (0.46) | MAOAMAOBDRD2KDM1ANPC1 | |
| SCHEMBL21054853 | 1.00 | MAOA (0.46) | MAOAMAOBDRD2KDM1ANPC1 | |
| SCHEMBL21053143 | 1.00 | MAOA (0.46) | MAOAMAOBDRD2KDM1ANPC1 | |
| SCHEMBL21092394 | 1.00 | MAOA (0.46) | MAOAMAOBDRD2KDM1ANPC1 | |
| SCHEMBL22657375 | 0.88 | ADRB2 (0.47) | MAOAMAOBKDM1ANPC1PKM | |
| SCHEMBL22657339 | 0.87 | MAOA (0.44) | MAOAMAOBKDM1ANPC1PKM | |
| SCHEMBL22657343 | 0.87 | MAOB (0.45) | MAOAMAOBKDM1ANPC1PKM | |
| SCHEMBL22657352 | 0.87 | MAOA (0.43) | MAOAMAOBKDM1ANPC1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11590089-B2 | Beta-2 selective adrenergic receptor agonists | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2023-02-28 | — | — | US | disclosed |
| US-20200360304-A1 | BETA-2 SELECTIVE ADRENERGIC RECEPTOR AGONISTS | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2020-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11590089-B2 | Beta-2 selective adrenergic receptor agonists | ADRB2, ADRB1, ADRA2C | MAOA 1468/4885MAOB 1029/4885DRD2 187/4885 |
| US-20200360304-A1 | BETA-2 SELECTIVE ADRENERGIC RECEPTOR AGONISTS | ADRB2, ADRB1, ADRA2C | MAOA 1468/4885MAOB 1029/4885DRD2 187/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.