Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | CPB1 | P15086 | 1/20 | 0.34 |
| ▸ | FABP4 | P15090 | 1/20 | 0.34 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22657363 | 0.89 | NPC1 (0.45) | NPC1RAB9APKMMAOAMAOB | |
| SCHEMBL22657334 | 0.83 | ADRB2 (0.59) | NPC1RAB9APKMADRB2MAOA | |
| SCHEMBL22657335 | 0.79 | KMT2A (0.40) | NPC1RAB9APKMMAOAMAOB | |
| SCHEMBL22657339 | 0.79 | MAOA (0.44) | NPC1RAB9APKMMAOAMAOB | |
| SCHEMBL22657362 | 0.78 | ADRB2 (0.52) | NPC1RAB9APKMADRB2MAOA | |
| SCHEMBL22657371 | 0.78 | ADRB2 (0.52) | NPC1RAB9APKMADRB2MAOA | |
| SCHEMBL30207384 | 0.78 | ADRB2 (0.52) | NPC1RAB9APKMADRB2MAOA | |
| SCHEMBL21091942 | 0.78 | ADRB2 (0.52) | NPC1RAB9APKMADRB2MAOA | |
| SCHEMBL22657360 | 0.78 | ADRB2 (0.52) | NPC1RAB9APKMADRB2MAOA | |
| SCHEMBL21054854 | 0.78 | MAOA (0.46) | NPC1RAB9APKMADRB2MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200360304-A1 | BETA-2 SELECTIVE ADRENERGIC RECEPTOR AGONISTS | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2020-11-19 | — | — | US | disclosed |
| US-20200360304-A1 | BETA-2 SELECTIVE ADRENERGIC RECEPTOR AGONISTS | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2020-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200360304-A1 | BETA-2 SELECTIVE ADRENERGIC RECEPTOR AGONISTS | ADRB2, ADRB1, ADRA2C | NPC1 1900/4885RAB9A 2534/4885PKM 2910/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.