Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | DDO | Q99489 | 1/20 | 0.37 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27922486 | 0.77 | MAOA (0.31) | — | |
| SCHEMBL22658219 | 0.77 | POLB (0.37) | KDM4E | |
| SCHEMBL30515544 | 0.77 | NOS1 (0.38) | NOS1 | |
| SCHEMBL15577863 | 0.77 | NOS1 (0.38) | NOS1 | |
| SCHEMBL23541061 | 0.74 | NOS1 (0.37) | KDM4EMEN1ALDH1A1LMNAKMT2A | |
| SCHEMBL347549 | 0.73 | HCAR2 (0.31) | — | |
| SCHEMBL7675347 | 0.73 | — | — | |
| SCHEMBL11803991 | 0.72 | ALDH1A1 (0.35) | KDM4EMEN1ALDH1A1LMNAKMT2A | |
| SCHEMBL27961462 | 0.72 | CYP11B2 (0.43) | KDM4EMEN1ALDH1A1LMNAKMT2A | |
| SCHEMBL28294266 | 0.72 | KDM4E (0.36) | KDM4EMEN1ALDH1A1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3983386-A1 | ACSS2 INHIBITORS AND METHODS OF USE THEREOF | Metabomed Ltd (IL) | 2022-04-20 | — | — | EP | disclosed |
| WO-2020230136-A1 | ACSS2 INHIBITORS AND METHODS OF USE THEREOF | METABOMED LTD (IL) | 2020-11-19 | — | — | WO | disclosed |