Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 1/20 | 0.39 |
| ▸ | XDH | P47989 | 1/20 | 0.34 |
| ▸ | DBH | P09172 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.31 |
| ▸ | ABAT | P80404 | 1/20 | 0.31 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | PLCG2 | P16885 | 1/20 | 0.30 |
| ▸ | IKBKB | O14920 | 1/20 | 0.30 |
| ▸ | CHUK | O15111 | 1/20 | 0.30 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27237602 | 0.83 | IKBKB (0.42) | FBP1XDHDBHAPEX1ALDH1A1 | |
| SCHEMBL30224871 | 0.83 | FBP1 (0.36) | FBP1XDHDBHAPEX1ALDH1A1 | |
| SCHEMBL18825065 | 0.77 | GPR84 (0.39) | FBP1ALDH1A1MAPTNPSR1LMNA | |
| SCHEMBL1423220 | 0.76 | TDP1 (0.43) | APEX1ALDH1A1VCAM1MAPTNPSR1 | |
| Ethoxycarbonyl Group SCHEMBL27809829 | 0.75 | FBP1 (0.33) | FBP1XDHALDH1A1MAPT | |
| SCHEMBL2768545 | 0.74 | GRIN2D (0.49) | APEX1ALDH1A1MAPTNPSR1MEN1 | |
| SCHEMBL30978917 | 0.74 | HRH4 (0.44) | FBP1ALDH1A1VCAM1PLCG2IKBKB | |
| SCHEMBL1983087 | 0.74 | S100A4 (0.40) | FBP1APEX1ALDH1A1MAPTNPSR1 | |
| SCHEMBL24988935 | 0.74 | LMNA (0.35) | FBP1XDHALDH1A1VCAM1MAPT | |
| SCHEMBL12697213 | 0.72 | CYP2A6 (0.38) | ALDH1A1MAPTBACE1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3983386-A1 | ACSS2 INHIBITORS AND METHODS OF USE THEREOF | Metabomed Ltd (IL) | 2022-04-20 | — | — | EP | disclosed |
| WO-2020230136-A1 | ACSS2 INHIBITORS AND METHODS OF USE THEREOF | METABOMED LTD (IL) | 2020-11-19 | — | — | WO | disclosed |