Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | XDH | P47989 | 1/20 | 0.35 |
| ▸ | FBP1 | P09467 | 1/20 | 0.34 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | PTGES | O14684 | 1/20 | 0.32 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.32 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CD38 | P28907 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30848965 | 0.78 | LMNA (0.38) | LMNAXDHFBP1F2RL3CHEK1 | |
| SCHEMBL27237592 | 0.77 | F2RL3 (0.41) | XDHFBP1F2RL3ALDH1A1MAPT | |
| SCHEMBL30848953 | 0.77 | F2RL3 (0.41) | XDHFBP1F2RL3ALDH1A1MAPT | |
| SCHEMBL30224929 | 0.76 | XDH (0.37) | LMNAXDHFBP1F2RL3CHEK1 | |
| SCHEMBL30224943 | 0.76 | F2RL3 (0.40) | LMNAXDHFBP1F2RL3CHEK1 | |
| SCHEMBL30224768 | 0.76 | LMNA (0.36) | LMNAFBP1F2RL3CHEK1ALDH1A1 | |
| SCHEMBL27237602 | 0.76 | IKBKB (0.42) | XDHFBP1ALDH1A1MAPT | |
| SCHEMBL30224871 | 0.76 | FBP1 (0.36) | XDHFBP1ALDH1A1MAPTHPGD | |
| SCHEMBL22658346 | 0.74 | FBP1 (0.39) | LMNAXDHFBP1ALDH1A1MAPT | |
| SCHEMBL30849019 | 0.74 | F2RL3 (0.42) | LMNAF2RL3CHEK1ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117794917-A | Novel indole derivatives, pharmaceutical compositions containing the same and uses thereof | 水疗免疫疗法有限公司 | 2024-03-29 | — | — | CN | disclosed |
| WO-2023013994-A1 | NOVEL INDOLE DERIVATIVE, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND USE THEREOF | 주식회사 미토이뮨테라퓨틱스 | 2023-02-09 | — | — | WO | disclosed |