SCHEMBL22665208

SCHEMBL22665208

Nc1cccc(C2=CC(c3ccccc3)CC=C2)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.44
MEN1 O00255 3/20 0.36
MAPT P10636 3/20 0.36
ALDH1A1 P00352 3/20 0.36
HPGD P15428 3/20 0.36
KDM4E B2RXH2 2/20 0.36
LMNA P02545 2/20 0.36
KMT2A Q03164 2/20 0.36
MECP2 P51608 1/20 0.36
MAP4K4 O95819 5/20 0.36
PSIP1 O75475 1/20 0.35
AXL P30530 1/20 0.35
MKNK1 Q9BUB5 1/20 0.35
MKNK2 Q9HBH9 1/20 0.35
GLA P06280 1/20 0.34
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34
ATAD2 Q6PL18 1/20 0.33
METAP2 P50579 1/20 0.33
NTRK1 P04629 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29678250 0.84 SLC18A3 (0.31) MAOAMAPTTSHR
SCHEMBL24689878 0.75 L3MBTL1 (0.33) MEN1MAPTALDH1A1HPGDKDM4E
SCHEMBL18960615 0.74 GABRG2 (0.38) MAOAMEN1MAPTALDH1A1HPGD
SCHEMBL18516507 0.72 ATM (0.32) ALDH1A1KDM4E
SCHEMBL5437594 0.72 MAOB (0.34) MAOAMAPTLMNATSHRHSD17B10
SCHEMBL26049475 0.70 HDAC4 (0.41) KDM4E
SCHEMBL21698968 0.70 MAOA (0.37) MAOAMEN1MAPTALDH1A1HPGD
SCHEMBL21425901 0.70 PLA2G2A (0.36) MEN1MAPTALDH1A1HPGDKDM4E
SCHEMBL19526654 0.70 MAOB (0.38) MAOAMEN1ALDH1A1HPGDKMT2A
SCHEMBL17705326 0.70 KDM1A (0.33) MAPTALDH1A1KDM4ENPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3739645-A2 ORGANIC LIGHT-EMITTING DEVICE Samsung Electronics Co., Ltd. (KR) 2020-11-18 EP disclosed