Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.37 |
| ▸ | NSD2 | O96028 | 1/20 | 0.37 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5928818 | 0.80 | MEN1 (0.50) | MAPTMEN1KMT2AKDM4ETHRB | |
| SCHEMBL28703458 | 0.80 | HTT (0.47) | HRH3EGFRMAPTMEN1KMT2A | |
| SCHEMBL28700508 | 0.78 | HTT (0.48) | HRH3EGFRMAPTMEN1KMT2A | |
| SCHEMBL22678453 | 0.77 | MAPT (0.41) | HPGDMAPTMEN1KMT2AKDM4E | |
| SCHEMBL22670353 | 0.76 | ACSS2 (0.48) | HPGDMAPTMEN1KMT2AKDM4E | |
| SCHEMBL29996539 | 0.73 | MAPT (0.52) | MAPTMEN1KMT2AKDM4EL3MBTL1 | |
| SCHEMBL29996730 | 0.71 | MAPT (0.53) | HPGDMAPTMEN1KMT2AKDM4E | |
| SCHEMBL22670032 | 0.71 | POLB (0.49) | HPGDMAPTMEN1KMT2AKDM4E | |
| SCHEMBL5928770 | 0.70 | MAPT (0.67) | MAPTMEN1KMT2AKDM4ETHRB | |
| SCHEMBL257928 | 0.68 | EGFR (0.48) | HPGDHRH3EGFRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020230136-A1 | ACSS2 INHIBITORS AND METHODS OF USE THEREOF | METABOMED LTD (IL) | 2020-11-19 | — | — | WO | disclosed |