Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.41 |
| ▸ | MEN1 | O00255 | 6/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | LOX | P28300 | 1/20 | 0.39 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.39 |
| ▸ | LOXL4 | Q96JB6 | 1/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22670353 | 0.88 | ACSS2 (0.48) | MAPTKMT2AMEN1KDM4ETHRB | |
| SCHEMBL5928818 | 0.85 | MEN1 (0.50) | MAPTKMT2AMEN1KDM4ETHRB | |
| SCHEMBL5928903 | 0.82 | MAPT (0.48) | MAPTKMT2AMEN1KDM4ETHRB | |
| SCHEMBL5713339 | 0.78 | LOX (0.63) | MAPTKMT2AMEN1KDM4ETHRB | |
| SCHEMBL28689709 | 0.77 | HTT (0.51) | MAPTKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL22670153 | 0.77 | HPGD (0.41) | MAPTKMT2AMEN1KDM4ETHRB | |
| SCHEMBL22670032 | 0.75 | POLB (0.49) | MAPTKMT2AMEN1KDM4ETHRB | |
| SCHEMBL29409974 | 0.70 | MAPT (0.55) | MAPTKMT2AMEN1KDM4EL3MBTL1 | |
| SCHEMBL28709911 | 0.69 | ACSS2 (0.49) | MAPTKMT2AMEN1ALDH1A1LOX | |
| SCHEMBL22671454 | 0.68 | MAPT (0.37) | MAPTKMT2AMEN1KDM4ETHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020230134-A1 | ACSS2 INHIBITORS AND METHODS OF USE THEREOF | METABOMED LTD (IL) | 2020-11-19 | — | — | WO | disclosed |