Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 7/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | ATM | Q13315 | 2/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | CCR6 | P51684 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 7/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | LOX | P28300 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22678453 | 0.88 | MAPT (0.41) | ACSS2MEN1KMT2AALDH1A1ATM | |
| SCHEMBL5928818 | 0.83 | MEN1 (0.50) | ACSS2MEN1KMT2AALDH1A1ATM | |
| SCHEMBL5928903 | 0.81 | MAPT (0.48) | MEN1KMT2AALDH1A1HTTLMNA | |
| SCHEMBL28709911 | 0.81 | ACSS2 (0.49) | ACSS2MEN1KMT2AALDH1A1ATM | |
| SCHEMBL28933622 | 0.78 | ACSS2 (0.59) | ACSS2MEN1KMT2AALDH1A1ATM | |
| SCHEMBL5928736 | 0.77 | MAPT (0.49) | MEN1KMT2AALDH1A1HTTLMNA | |
| SCHEMBL5713339 | 0.77 | LOX (0.63) | MEN1KMT2AALDH1A1ATMHTT | |
| SCHEMBL22670153 | 0.76 | HPGD (0.41) | MEN1KMT2AALDH1A1HPGDMAPT | |
| SCHEMBL28685650 | 0.75 | ACSS2 (0.56) | ACSS2MEN1KMT2AALDH1A1ATM | |
| SCHEMBL22670032 | 0.74 | POLB (0.49) | MEN1KMT2AALDH1A1HPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020230136-A1 | ACSS2 INHIBITORS AND METHODS OF USE THEREOF | METABOMED LTD (IL) | 2020-11-19 | — | — | WO | disclosed |