SCHEMBL2267119

SCHEMBL2267119

CCN[SiH2]CCCc1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
SIGMAR1 Q99720 8/20 0.45
CHRM2 P08172 1/20 0.44
HTR1A P08908 1/20 0.44
ADRA2A P08913 1/20 0.44
CHRM1 P11229 1/20 0.44
DRD1 P21728 1/20 0.44
SLC6A2 P23975 1/20 0.44
SLC6A4 P31645 1/20 0.44
ADRA1A P35348 1/20 0.44
OPRM1 P35372 1/20 0.44
DRD3 P35462 1/20 0.44
SLC6A3 Q01959 1/20 0.44
KCNH2 Q12809 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2102172 0.86 L3MBTL1 (0.44) MEN1KMT2AL3MBTL1SIGMAR1CHRM2
SCHEMBL2100487 0.81 KCNH2 (0.54) MEN1KMT2AL3MBTL1SIGMAR1CHRM2
SCHEMBL2267574 0.80 L3MBTL1 (0.53) MEN1KMT2AL3MBTL1SIGMAR1
SCHEMBL8964010 0.77 L3MBTL1 (0.48) MEN1KMT2AL3MBTL1SIGMAR1CHRM2
SCHEMBL15150830 0.72 MEN1 (0.48) MEN1KMT2AL3MBTL1SIGMAR1CHRM2
SCHEMBL1882499 0.72 MAOA (0.58) L3MBTL1SIGMAR1ADRA1ASLC6A3
SCHEMBL6546196 0.70 HTR2A (0.60) MEN1KMT2AL3MBTL1SIGMAR1CHRM2
Butylbenzyl SCHEMBL28449927 0.70 SIGMAR1 (0.55) MEN1KMT2AL3MBTL1SIGMAR1CHRM2
SCHEMBL8136862 0.69 IDO1 (0.47) MEN1KMT2AL3MBTL1SIGMAR1CHRM2
SCHEMBL3441609 0.69 SIGMAR1 (0.75) MEN1KMT2ASIGMAR1DRD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8404584-B2 Method of manufacturing semiconductor device FUJITSU LIMITED (JP) 2013-03-26 US disclosed
US-20110207319-A1 METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2011-08-25 US disclosed