Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | DRD1 | P21728 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8384814 | 0.85 | ALDH1A1 (0.48) | L3MBTL1MAOAKCNH2AOC3MAOB | |
| Hydrochloric Acid SCHEMBL4465538 | 0.83 | ALDH1A1 (0.46) | L3MBTL1MEN1KMT2AMAOAAOC3 | |
| Hydrochloric Acid SCHEMBL4465542 | 0.83 | ALDH1A1 (0.46) | L3MBTL1MEN1KMT2AMAOAAOC3 | |
| SCHEMBL1882499 | 0.80 | MAOA (0.58) | L3MBTL1SIGMAR1MAOAADRA1ASLC6A3 | |
| SCHEMBL7584653 | 0.77 | TAAR1 (0.46) | L3MBTL1CHRM2ADRA2ACHRM1SLC6A2 | |
| SCHEMBL8136862 | 0.77 | IDO1 (0.47) | L3MBTL1MEN1KMT2ASIGMAR1MAOA | |
| SCHEMBL2267119 | 0.77 | MEN1 (0.46) | L3MBTL1MEN1KMT2ASIGMAR1CHRM2 | |
| SCHEMBL2272071 | 0.76 | SIGMAR1 (0.48) | L3MBTL1SIGMAR1MAOAADRA1ASLC6A3 | |
| SCHEMBL8766061 | 0.76 | HDAC3 (0.50) | SIGMAR1MAOAADRA1ASLC6A3MAOB | |
| SCHEMBL8766068 | 0.76 | HDAC3 (0.50) | SIGMAR1MAOAADRA1ASLC6A3MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0707845-A2 | Alkylmethylsiloxane-containing gels | DOW CORNING CORPORATION (US) | 1996-04-24 | — | — | EP | disclosed |
| US-5480637-A | CONTAINING HYDROXYSTEARIC ACID GELATOR, SILOXANE OIL, AN ALKYLMETHYLSILOXANE POLYMER OR COPOLYMER; INCREASED GEL STRENGTH, FIRMNESS, RIGIDITY; ANTIPERSPIRANT | DOW CORNING CORPORATION (US) | 1996-01-02 | — | — | US | disclosed |