Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA5A | P35218 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | FLT3 | P36888 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22396834 | 0.84 | MRGPRX4 (0.49) | LMNAMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL11001655 | 0.83 | LMNA (0.44) | LMNAMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL8282264 | 0.82 | CA2 (0.40) | LMNAMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL11002262 | 0.81 | MAPT (0.48) | LMNAMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL15092023 | 0.81 | KMT2A (0.47) | LMNAMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL23558705 | 0.81 | ELANE (0.43) | LMNAMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL11004782 | 0.79 | MAPT (0.49) | LMNAMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL11005433 | 0.79 | LMNA (0.41) | LMNAMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL23558706 | 0.78 | ELANE (0.47) | LMNAMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL23558707 | 0.78 | KMT2A (0.36) | LMNAMAPTALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9174979-B2 | Phenanthroindolizidine compound and NFκB inhibitor containing same as active ingredient | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 2015-11-03 | — | — | US | disclosed |
| EP-2351754-B1 | PHENANTHROINDOLIZIDINE COMPOUND AND NF kB INHIBITOR CONTAINING SAME AS ACTIVE INGREDIENT | YAKULT HONSHA KK (JP) | 2015-06-24 | — | — | EP | disclosed |
| US-20110201638-A1 | PHENANTHROINDOLIZIDINE COMPOUND AND NFkB INHIBITOR CONTAINING SAME AS ACTIVE INGREDIENT | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 2011-08-18 | — | — | US | disclosed |
| EP-2351754-A1 | PHENANTHROINDOLIZIDINE COMPOUND AND NF B INHIBITOR CONTAINING SAME AS ACTIVE INGREDIENT | Kabushiki Kaisha Yakult Honsha (JP) | 2011-08-03 | — | — | EP | disclosed |
| US-7585891-B2 | 5-(3,3-Dichloroprop-2-enyloxy)-2-[4-(2,2-dimethylbenzo[d]1,3-dioxolan-4-yloxy)butoxy]-1,3-dichlorobenzene; acaricides | FMC CORPORATION (US) | 2009-09-08 | — | — | US | disclosed |
| US-7585891-B2 | 5-(3,3-Dichloroprop-2-enyloxy)-2-[4-(2,2-dimethylbenzo[d]1,3-dioxolan-4-yloxy)butoxy]-1,3-dichlorobenzene; acaricides | FMC CORPORATION (US) | 2009-09-08 | — | — | US | disclosed |
| US-7585891-B2 | 5-(3,3-Dichloroprop-2-enyloxy)-2-[4-(2,2-dimethylbenzo[d]1,3-dioxolan-4-yloxy)butoxy]-1,3-dichlorobenzene; acaricides | FMC CORPORATION (US) | 2009-09-08 | — | — | US | disclosed |
| EP-1622889-A4 | PESTICIDAL (DIHALOPROPENYL)PHENYLALKYL SUBSTITUTED BENZODIOXOLANE AND BENZODIOXOLE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2008-01-16 | — | — | EP | disclosed |
| US-20060247283-A1 | Pesticidal (dihalopropenyl)phenylalkyl substituted benzodioxolane and benzodioxole derivatives | FMC CORPORATION | 2006-11-02 | — | — | US | disclosed |
| EP-1622889-A2 | PESTICIDAL (DIHALOPROPENYL)PHENYLALKYL SUBSTITUTED BENZODIOXOLANE AND BENZODIOXOLE DERIVATIVES | FMC CORPORATION (US) | 2006-02-08 | — | — | EP | disclosed |
| WO-2004098284-A2 | PESTICIDAL (DIHALOPROPENYL)PHENYLALKYL SUBSTITUTED BENZODIOXOLANE AND BENZODIOXOLE DERIVATIVES | FMC CORPORATION (US) | 2004-11-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110201638-A1 | PHENANTHROINDOLIZIDINE COMPOUND AND NFkB INHIBITOR CONTAINING SAME AS ACTIVE INGREDIENT | NFKBIA, NFKB2, NFKB1 | LMNA 1741/4885MAPT 3802/4885ALDH1A1 2881/4885 |
| US-20060247283-A1 | Pesticidal (dihalopropenyl)phenylalkyl substituted benzodioxolane and benzodioxole derivatives | DDT, BBOX1, PDHX | LMNA 2673/4885MAPT 4703/4885ALDH1A1 606/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.