SCHEMBL2267244

SCHEMBL2267244

CCOS(=O)(=O)c1ccc(F)cc1

nearest known ligand 0.49

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.45
CA2 P00918 2/20 0.45
MMP1 P03956 1/20 0.45
MMP2 P08253 1/20 0.45
MMP9 P14780 1/20 0.45
MMP8 P22894 1/20 0.45
MMP13 P45452 1/20 0.45
L3MBTL1 Q9Y468 2/20 0.44
KMT2A Q03164 3/20 0.43
MEN1 O00255 2/20 0.43
PTGS2 P35354 2/20 0.42
TSHR P16473 1/20 0.42
MAPK1 P28482 1/20 0.42
HSD17B10 Q99714 1/20 0.42
ALDH1A1 P00352 3/20 0.42
SOS1 Q07889 1/20 0.41
HTT P42858 1/20 0.41
PTGS1 P23219 1/20 0.41
PKM P14618 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluorobenzene SCHEMBL27930268 0.84 KMT2A (0.43) CA1CA2L3MBTL1KMT2AMEN1
SCHEMBL19809912 0.84 L3MBTL1 (0.45) CA1CA2MMP1MMP2MMP9
SCHEMBL196957 0.83 SMN1; SMN2 (0.47) CA1CA2L3MBTL1KMT2AMEN1
SCHEMBL6114697 0.83 MEN1 (0.46) CA1CA2MMP1MMP2MMP9
SCHEMBL15000837 0.83 MEN1 (0.46) CA1CA2MMP1MMP2MMP9
SCHEMBL27670053 0.81 CA2 (0.46) CA1CA2MMP1MMP9MMP13
SCHEMBL28996978 0.81 ENPP2 (0.46) CA1CA2PTGS2PTGS1
SCHEMBL76249 0.81 GAA (0.50) CA1CA2MMP1MMP2MMP9
SCHEMBL552333 0.81 GAA (0.57) CA1CA2MMP1MMP2MMP9
SCHEMBL1472371 0.80 RECQL (0.50) CA1CA2L3MBTL1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3276735-B1 NONAQUEOUS ELECTROLYTE FOR SODIUM SECONDARY BATTERY AND SODIUM SECONDARY BATTERY SUMITOMO CHEMICAL CO (JP) 2023-07-12 EP disclosed
CN-107431246-B Nonaqueous electrolyte for sodium secondary battery and sodium secondary battery 住友化学株式会社 2021-03-09 CN disclosed
EP-2827433-B1 SECONDARY BATTERY ELECTROLYTE AND SECONDARY BATTERY USING SAME ENVISION AESC ENERGY DEVICES LTD (JP) 2019-09-25 EP disclosed
US-20180123170-A1 NONAQUEOUS ELECTROLYTE FOR SODIUM SECONDARY BATTERY AND SODIUM SECONDARY BATTERY SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-05-03 US disclosed
EP-3276735-A1 NONAQUEOUS ELECTROLYTE FOR SODIUM SECONDARY CELL, AND SODIUM SECONDARY CELL Sumitomo Chemical Company, Ltd. (JP) 2018-01-31 EP disclosed
US-8389564-B2 Proteasome inhibitors TRIPHASE RESEARCH AND DEVELOPMENT I CORP. (CA) 2013-03-05 US disclosed
US-20120270919-A1 PROTEASOME INHIBITORS NEREUS PHARMACEUTICALS, INC. (US) 2012-10-25 US disclosed
US-8227503-B2 Proteasome inhibitors NEREUS PHARMACEUTICALS, INC. (US) 2012-07-24 US disclosed
CN-102187511-A Nonaqueous electrolyte, and nonaqueous electrolyte secondary battery using same PANASONIC CORP 2011-09-14 CN disclosed
US-20110200886-A1 NON-AQUEOUS ELECTROLYTE AND NON-AQUEOUS ELECTROLYTE SECONDARY BATTERY USING THE SAME PANASONIC CORPORATION (JP) 2011-08-18 US disclosed
US-20090298906-A1 PROTEASOME INHIBITORS NEREUS PHARMACEUTICALS, INC. (US) 2009-12-03 US disclosed
CN-100475803-C Heterocyclic onium salt WAKO PURE CHEM IND LTD (JP) 2009-04-08 CN disclosed
US-7485641-B2 Substituted 3-amino-pyrrolidino-4-lactams PFIZER, INC. (US) 2009-02-03 US disclosed
CN-100418947-C Hybrid onium salts WAKO PURE CHEM IND LTD (JP) 2008-09-17 CN disclosed
US-20070299076-A1 Substituted 3-Amino-Pyrrolidino-4-Lactams PFIZER INC 2007-12-27 US disclosed
CN-1295211-C Process for producing aminoalkylsulfonic acid and method of salt exchange for salt thereof WAKO PURE CHEM IND LTD (JP) 2007-01-17 CN disclosed
CN-1854133-A Heterocycle-bearing onium salts WAKO PURE CHEM IND LTD (JP) 2006-11-01 CN disclosed
CN-1678574-A Process for producing aminoalkylsulfonic acid and method of salt exchange for salt thereof WAKO PURE CHEM IND LTD (JP) 2005-10-05 CN disclosed
CN-1622943-A Heterocyclic onium salt WAKO PURE CHEM IND LTD (JP) 2005-06-01 CN disclosed
CN-1578766-A Hybrid onium salt WAKO PURE CHEM IND LTD (JP) 2005-02-09 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120270919-A1 PROTEASOME INHIBITORS PSMB1, PSME1, PSME3 CA1 3708/4885CA2 4532/4885MMP1 2572/4885
US-20070299076-A1 Substituted 3-Amino-Pyrrolidino-4-Lactams PRMT1, PRMT7, PRMT3 CA1 3075/4885CA2 3033/4885MMP1 3577/4885
US-20090298906-A1 PROTEASOME INHIBITORS PSMB1, PSME1, PSME3 CA1 3708/4885CA2 4532/4885MMP1 2572/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.