Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.47 |
| ▸ | HTT | P42858 | 5/20 | 0.47 |
| ▸ | TP53 | P04637 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 7/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | USP7 | Q93009 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.35 |
| ▸ | USP2 | O75604 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | ALPL | P05186 | 2/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14344581 | 0.85 | LMNA (0.49) | LMNAHTTTP53MAPK1TSHR | |
| SCHEMBL2270967 | 0.81 | LMNA (0.47) | LMNAHTTTP53MAPK1TSHR | |
| SCHEMBL265448 | 0.80 | LMNA (0.53) | LMNAHTTTP53MAPK1TSHR | |
| SCHEMBL2367335 | 0.78 | LMNA (0.45) | LMNAHTTTP53MAPK1TSHR | |
| SCHEMBL3924756 | 0.75 | TDP1 (0.32) | KMT2AMAPTNPSR1TDP1 | |
| SCHEMBL2977142 | 0.75 | LMNA (0.41) | LMNAHTTTP53MAPK1TSHR | |
| SCHEMBL3919770 | 0.74 | TP53 (0.71) | LMNAHTTTP53TSHRMEN1 | |
| Hydrochloric Acid SCHEMBL2271003 | 0.73 | LMNA (0.69) | LMNAHTTTP53TSHRMEN1 | |
| SCHEMBL7441492 | 0.71 | MAPT (0.40) | LMNAHTTTP53MEN1KMT2A | |
| SCHEMBL11689320 | 0.71 | LMNA (0.41) | LMNAHTTTP53MAPK1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8258169-B2 | Pyrazole-4-N-alkoxycarboxamides as microbiocides | SYNGENTA CROP PROTECTION, LLC (US) | 2012-09-04 | — | — | US | disclosed |
| US-8258169-B2 | Pyrazole-4-N-alkoxycarboxamides as microbiocides | SYNGENTA CROP PROTECTION, LLC (US) | 2012-09-04 | — | — | US | disclosed |
| US-20110230537-A1 | NOVEL PYRAZOLE-4-N-ALKOXYCARBOXAMIDES AS MICROBIOCIDES | SYNGENTA CROP PROTECTION LLC (US) | 2011-09-22 | — | — | US | disclosed |
| US-20110230537-A1 | NOVEL PYRAZOLE-4-N-ALKOXYCARBOXAMIDES AS MICROBIOCIDES | SYNGENTA CROP PROTECTION LLC (US) | 2011-09-22 | — | — | US | disclosed |
| EP-2364293-A2 | NOVEL MICROBIOCIDES | Syngenta Participations AG (CH) | 2011-09-14 | — | — | EP | disclosed |
| US-20110207771-A1 | N-(L-ALKYL-2-PHENYLETHYL)-CARBOXAMIDE DERIVATIVES AND USE THEREOF AS FUNGICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2011-08-25 | — | — | US | disclosed |
| US-20110207771-A1 | N-(L-ALKYL-2-PHENYLETHYL)-CARBOXAMIDE DERIVATIVES AND USE THEREOF AS FUNGICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2011-08-25 | — | — | US | disclosed |
| US-20110207771-A1 | N-(L-ALKYL-2-PHENYLETHYL)-CARBOXAMIDE DERIVATIVES AND USE THEREOF AS FUNGICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2011-08-25 | — | — | US | disclosed |
| WO-2010063700-A2 | NOVEL MICROBIOCIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2010-06-10 | — | — | WO | disclosed |
| WO-2010063700-A2 | NOVEL MICROBIOCIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2010-06-10 | — | — | WO | disclosed |
| EP-2035374-A1 | N- (L-ALKYL-2- PHENYLETHYL) -CARBOXAMIDE DERIVATIVES AND USE THEREOF AS FUNGICIDES | Syngeta Participations AG (CH) | 2009-03-18 | — | — | EP | disclosed |
| WO-2007141009-A1 | N- (L-ALKYL-2- PHENYLETHYL) -CARBOXAMIDE DERIVATIVES AND USE THEREOF AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2007-12-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110230537-A1 | NOVEL PYRAZOLE-4-N-ALKOXYCARBOXAMIDES AS MICROBIOCIDES | CASP1, CASP14, CD14 | LMNA 3949/4885HTT 4878/4885TP53 3773/4885 |
| US-20110207771-A1 | N-(L-ALKYL-2-PHENYLETHYL)-CARBOXAMIDE DERIVATIVES AND USE THEREOF AS FUNGICIDES | CYP1A1, CYP51A1, CYP2E1 | LMNA 3319/4885HTT 4044/4885TP53 3831/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.