Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.41 |
| ▸ | HTT | P42858 | 4/20 | 0.41 |
| ▸ | TP53 | P04637 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 2/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2367335 | 0.78 | LMNA (0.45) | LMNAHTTTP53MAPK1TSHR | |
| SCHEMBL2982000 | 0.78 | LMNA (0.61) | LMNAHTTTP53TDP1MEN1 | |
| SCHEMBL8623864 | 0.78 | CASR (0.39) | LMNAHTTTP53MAPK1TDP1 | |
| SCHEMBL2267272 | 0.75 | LMNA (0.47) | LMNAHTTTP53MAPK1TSHR | |
| SCHEMBL2270967 | 0.75 | LMNA (0.47) | LMNAHTTTP53MAPK1TSHR | |
| SCHEMBL7441492 | 0.74 | MAPT (0.40) | LMNAHTTTP53MEN1KMT2A | |
| SCHEMBL7861796 | 0.74 | LMNA (0.53) | LMNAHTTTP53TDP1MEN1 | |
| SCHEMBL265448 | 0.74 | LMNA (0.53) | LMNAHTTTP53MAPK1TSHR | |
| SCHEMBL8629375 | 0.70 | TDP1 (0.45) | TP53MAPK1TDP1MEN1KMT2A | |
| SCHEMBL8625790 | 0.69 | PRMT1 (0.43) | LMNATP53TDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2155686-B1 | PYRAZOLE CARBOXYLIC ACID AMIDES USEFUL AS MICROBIOCIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2013-07-17 | — | — | EP | disclosed |
| EP-2155686-B1 | PYRAZOLE CARBOXYLIC ACID AMIDES USEFUL AS MICROBIOCIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2013-07-17 | — | — | EP | disclosed |
| US-8304444-B2 | Pyrazole carboxylic acid amides useful as microbiocides | SYNGENTA CROP PROTECTION, LLC (US) | 2012-11-06 | — | — | US | disclosed |
| US-8304444-B2 | Pyrazole carboxylic acid amides useful as microbiocides | SYNGENTA CROP PROTECTION, LLC (US) | 2012-11-06 | — | — | US | disclosed |
| US-20100173966-A1 | PYRAZOLE CARBOXYLIC ACID AMIDES USEFUL AS MICROBIOCIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-07-08 | — | — | US | disclosed |
| US-20100173966-A1 | PYRAZOLE CARBOXYLIC ACID AMIDES USEFUL AS MICROBIOCIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-07-08 | — | — | US | disclosed |
| EP-2155686-A1 | PYRAZOLE CARBOXYLIC ACID AMIDES USEFUL AS MICROBIOCIDES | Syngeta Participations AG (CH) | 2010-02-24 | — | — | EP | disclosed |
| WO-2008148570-A1 | PYRAZOLE CARBOXYLIC ACID AMIDES USEFUL AS MICROBIOCIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2008-12-11 | — | — | WO | disclosed |
| WO-2008148570-A1 | PYRAZOLE CARBOXYLIC ACID AMIDES USEFUL AS MICROBIOCIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2008-12-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100173966-A1 | PYRAZOLE CARBOXYLIC ACID AMIDES USEFUL AS MICROBIOCIDES | ARG1, FPR1, ARG2 | LMNA 4817/4885HTT 4868/4885TP53 1747/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.