Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.51 |
| ▸ | OPRL1 | P41146 | 5/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | DPP4 | P27487 | 1/20 | 0.48 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.47 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.47 |
| ▸ | DRD1 | P21728 | 1/20 | 0.47 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2267354 | 1.00 | L3MBTL3 (0.53) | L3MBTL3L3MBTL1KCNA3OPRL1OPRM1 | |
| SCHEMBL5745425 | 0.89 | KDM4E (0.55) | L3MBTL3L3MBTL1KCNA3OPRL1OPRM1 | |
| SCHEMBL5745466 | 0.89 | SLC6A9 (0.47) | L3MBTL3L3MBTL1KCNA3OPRL1OPRM1 | |
| SCHEMBL5745201 | 0.89 | L3MBTL3 (0.61) | L3MBTL3L3MBTL1KCNA3OPRL1OPRM1 | |
| Hydrochloric Acid SCHEMBL10797918 | 0.87 | L3MBTL3 (0.59) | L3MBTL3L3MBTL1KCNA3OPRL1OPRM1 | |
| SCHEMBL48800 | 0.84 | OPRM1 (0.48) | L3MBTL3L3MBTL1KCNA3OPRL1OPRM1 | |
| SCHEMBL5746042 | 0.83 | OPRL1 (0.51) | L3MBTL3L3MBTL1KCNA3OPRL1OPRM1 | |
| Hydrochloric Acid SCHEMBL741583 | 0.82 | OPRM1 (0.47) | L3MBTL3L3MBTL1KCNA3OPRL1OPRM1 | |
| SCHEMBL19281773 | 0.82 | OPRM1 (0.47) | L3MBTL3L3MBTL1KCNA3OPRL1OPRM1 | |
| SCHEMBL5240530 | 0.82 | KCNA3 (0.49) | L3MBTL3L3MBTL1KCNA3OPRL1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1693364-B1 | INTERMEDIATES FOR THE PRODUCTION OF OPTICALLY ACTIVE CYCLOPROPYLAMINE DERIVATIVES AND PROCESS FOR THE PRODUCTION OF THE INTERMEDIATES | DAIICHI SANKYO CO LTD (JP) | 2015-05-20 | — | — | EP | disclosed |
| US-7994344-B2 | Intermediates for the production of optically active cyclopropylamine derivatives and process for the production of the intermediates | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2011-08-09 | — | — | US | disclosed |
| US-20090240066-A1 | INTERMEDIATES FOR THE PRODUCTION OF OPTICALLY ACTIVE CYCLOPROPYLAMINE DERIVATIVES AND PROCESS FOR THE PRODUCTION OF THE INTERMEDIATES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2009-09-24 | — | — | US | disclosed |
| US-7569599-B2 | Intermediates for the production of optically active cyclopropylamine derivatives and process for the production of the intermediates | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2009-08-04 | — | — | US | disclosed |
| US-20070117988-A1 | Intermediates for the production of optically active cyclopropylamine derivatives and process for the production of the intermediates | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2007-05-24 | — | — | US | disclosed |
| EP-1693364-A1 | INTERMEDIATES FOR THE PRODUCTION OF OPTICALLY ACTIVE CYCLOPROPYLAMINE DERIVATIVES AND PROCESS FOR THE PRODUCTION OF THE INTERMEDIATES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-08-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070117988-A1 | Intermediates for the production of optically active cyclopropylamine derivatives and process for the production of the intermediates | RAP1A, RHOA, MGMT | L3MBTL3 2636/4885L3MBTL1 3585/4885KCNA3 602/4885 |
| US-20090240066-A1 | INTERMEDIATES FOR THE PRODUCTION OF OPTICALLY ACTIVE CYCLOPROPYLAMINE DERIVATIVES AND PROCESS FOR THE PRODUCTION OF THE INTERMEDIATES | RAP1A, RHOA, MGMT | L3MBTL3 2636/4885L3MBTL1 3585/4885KCNA3 602/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.