Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 3/20 | 0.47 |
| ▸ | CNR2 | P34972 | 3/20 | 0.47 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.46 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5745187 | 0.90 | KDM4E (0.47) | KDM4EL3MBTL3L3MBTL1ALDH1A1OPRL1 | |
| SCHEMBL2267354 | 0.89 | L3MBTL3 (0.53) | KDM4EL3MBTL3L3MBTL1ALDH1A1OPRL1 | |
| SCHEMBL2267306 | 0.89 | L3MBTL3 (0.53) | KDM4EL3MBTL3L3MBTL1ALDH1A1OPRL1 | |
| SCHEMBL5746014 | 0.83 | ALDH1A1 (0.46) | KDM4EALDH1A1OPRL1OPRM1OPRK1 | |
| SCHEMBL48800 | 0.81 | OPRM1 (0.48) | L3MBTL3L3MBTL1ALDH1A1OPRL1OPRM1 | |
| SCHEMBL5745466 | 0.80 | SLC6A9 (0.47) | L3MBTL3L3MBTL1ALDH1A1OPRL1OPRM1 | |
| SCHEMBL19281773 | 0.80 | OPRM1 (0.47) | L3MBTL3L3MBTL1ALDH1A1OPRL1OPRM1 | |
| Hydrochloric Acid SCHEMBL741583 | 0.80 | OPRM1 (0.47) | L3MBTL3L3MBTL1ALDH1A1OPRL1OPRM1 | |
| SCHEMBL18634599 | 0.79 | L3MBTL3 (0.50) | L3MBTL3L3MBTL1ALDH1A1OPRL1OPRM1 | |
| SCHEMBL18614900 | 0.79 | L3MBTL3 (0.50) | L3MBTL3L3MBTL1ALDH1A1OPRL1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1288198-B1 | PROCESS FOR THE PRODUCTION OF SULFONIC ESTERS | KANEKA CORP (JP) | 2006-12-20 | — | — | EP | disclosed |
| US-6992205-B2 | Process for the production of sulfonic esters | KANEKA CORPORATION (JP) | 2006-01-31 | — | — | US | disclosed |
| US-6864372-B2 | Process for the production of sulfonic esters | KANEKA CORPORATION (JP) | 2005-03-08 | — | — | US | disclosed |
| US-6794519-B2 | Process for the production of sulfonic esters | KANEKA CORPORATION (JP) | 2004-09-21 | — | — | US | disclosed |
| US-20030176713-A1 | Reacting an amino alcohol derivative with organic sulfonyl halide in a mixed solvent composed of an aprotic organic solvent and water in presence of a non-water prohibiting inorganic base | KANEKA CORPORATION (JP) | 2003-09-18 | — | — | US | disclosed |
| US-20030176711-A1 | Process for the production of sulfonic esters | KANEKA CORPORATION (JP) | 2003-09-18 | — | — | US | disclosed |
| US-20030162966-A1 | PROCESS FOR THE PRODUCTION OF SULFONIC ESTERS | KANEKA CORPORATION (JP) | 2003-08-28 | — | — | US | disclosed |
| EP-1288198-A1 | PROCESS FOR THE PRODUCTION OF SULFONIC ESTERS | KANEKA CORPORATION (JP) | 2003-03-05 | — | — | EP | disclosed |
| EP-0529702-B1 | Dihydropyridine derivatives, their preparation and their use | SANKYO CO (JP) | 1996-12-11 | — | — | EP | disclosed |
| EP-0529702-A1 | Dihydropyridine derivatives, their preparation and their use | Sankyo Company Limited (JP) | 1993-03-03 | — | — | EP | disclosed |
| CN-1017897-B | DIHYDROPYRIDINE DERIVATIVES, THEIR PREPARATION AND THEIR USE | SANKYO CO (JP) | 1992-08-19 | — | — | CN | disclosed |
| US-4772596-A | CALCIUM BLOCKERS | SANKYO COMPANY LIMITED (JP) | 1988-09-20 | — | — | US | disclosed |
| EP-0266922-A1 | Dihydropyridine derivatives, their preparation and their use | Sankyo Company Limited (JP) | 1988-05-11 | — | — | EP | disclosed |
| CN-87107150-A | Dihydrogen pyridine derivative and its production and use | — | 1988-05-04 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030162966-A1 | PROCESS FOR THE PRODUCTION OF SULFONIC ESTERS | TST, STS, SELENOI | KDM4E 2811/4885L3MBTL3 3743/4885L3MBTL1 3101/4885 |
| US-20030176711-A1 | Process for the production of sulfonic esters | TST, STS, SELENOI | KDM4E 2811/4885L3MBTL3 3743/4885L3MBTL1 3101/4885 |
| US-20030176713-A1 | Reacting an amino alcohol derivative with organic sulfonyl halide in a mixed solvent composed of an aprotic organic solvent and water in presence of a non-water prohibiting inorganic base | BRAF, ADH1C, TST | KDM4E 3216/4885L3MBTL3 2560/4885L3MBTL1 2186/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.