SCHEMBL2267732

SCHEMBL2267732

C=C[Si](NC)(c1ccccc1)C(C)C

nearest known ligand 0.31

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.31
TAAR1 Q96RJ0 3/20 0.31
KCNH3 Q9ULD8 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
SLC18A2 Q05940 1/20 0.31
SIGMAR1 Q99720 1/20 0.31
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2275369 0.82 ALDH1A1 (0.31) ALDH1A1TAAR1MEN1KMT2ASLC18A2
SCHEMBL2275031 0.81 SIGMAR1 (0.34) TAAR1MEN1KMT2ASIGMAR1
SCHEMBL2267447 0.72 SIGMAR1 (0.33) TAAR1MEN1KMT2ASIGMAR1
SCHEMBL2269681 0.71 ALDH1A1 (0.33) ALDH1A1
SCHEMBL2104427 0.71 ALDH1A1 (0.33) ALDH1A1TDP1
SCHEMBL2099888 0.69 TDP1 (0.36) ALDH1A1TAAR1KCNH3MEN1KMT2A
SCHEMBL2267663 0.69 TDP1 (0.36) ALDH1A1TAAR1KCNH3MEN1KMT2A
SCHEMBL2101781 0.68 TSHR (0.31) ALDH1A1
SCHEMBL2268083 0.68 ALDH1A1 (0.31) ALDH1A1
SCHEMBL2100673 0.65 TAAR1 (0.33) TAAR1MEN1KMT2ASLC18A2SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8404584-B2 Method of manufacturing semiconductor device FUJITSU LIMITED (JP) 2013-03-26 US disclosed
US-20110207319-A1 METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2011-08-25 US disclosed