Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | AKT1 | P31749 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.30 |
| ▸ | IDH1 | O75874 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL157867 | 0.81 | ALDH1A1 (0.36) | ALDH1A1TSHRAKT1IDH1 | |
| SCHEMBL2269062 | 0.78 | KCNN4 (0.33) | ALDH1A1TSHRAKT1HDAC8KCNN4 | |
| SCHEMBL2104427 | 0.77 | ALDH1A1 (0.33) | ALDH1A1TSHRESR1ESR2HDAC8 | |
| SCHEMBL2101781 | 0.74 | TSHR (0.31) | ALDH1A1TSHRAKT1 | |
| SCHEMBL22733960 | 0.72 | ALDH1A1 (0.34) | ALDH1A1TSHRIDH1 | |
| SCHEMBL2267732 | 0.71 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL2273625 | 0.71 | ALDH1A1 (0.31) | ALDH1A1KCNN4 | |
| SCHEMBL453982 | 0.69 | NR1H2 (0.48) | ALDH1A1TSHRAKT1ESR1ESR2 | |
| SCHEMBL160355 | 0.69 | ESR1 (0.39) | ALDH1A1TSHRAKT1ESR1ESR2 | |
| SCHEMBL2524118 | 0.69 | ESR1 (0.39) | ALDH1A1TSHRAKT1ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8404584-B2 | Method of manufacturing semiconductor device | FUJITSU LIMITED (JP) | 2013-03-26 | — | — | US | disclosed |
| US-20110207319-A1 | METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE | FUJITSU LIMITED (JP) | 2011-08-25 | — | — | US | disclosed |