Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24434035 | 0.73 | PIK3CA (0.42) | KDM4EALDH1A1MAPTMAPK1GAA | |
| SCHEMBL29924912 | 0.73 | HSD17B10 (0.44) | KDM4EALDH1A1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL29924734 | 0.70 | HSD17B10 (0.41) | KDM4EALDH1A1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL6774504 | 0.69 | HSD17B10 (0.42) | KDM4EALDH1A1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL6306238 | 0.67 | MAPT (0.38) | KDM4EALDH1A1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL24401142 | 0.67 | ALDH1A1 (0.36) | KDM4EALDH1A1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL27286488 | 0.65 | HSD17B10 (0.43) | KDM4EALDH1A1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL29924614 | 0.65 | CSNK2A2 (0.42) | KDM4ECYP1A2ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL25978729 | 0.65 | TSHR (0.41) | KDM4EALDH1A1SMN1; SMN2MAPTKMT2A | |
| SCHEMBL24401144 | 0.65 | MAPT (0.36) | KDM4EALDH1A1SMN1; SMN2MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3157904-B1 | ANTI-INFECTIVE COMPOUNDS | PASTEUR INSTITUT KOREA (KR) | 2020-11-18 | — | — | EP | disclosed |