Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.48 |
| ▸ | CRHBP | P24387 | 1/20 | 0.47 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | F10 | P00742 | 1/20 | 0.46 |
| ▸ | PLG | P00747 | 1/20 | 0.46 |
| ▸ | PLAU | P00749 | 1/20 | 0.46 |
| ▸ | PLAT | P00750 | 1/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.46 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2437022 | 0.88 | CRHBP (0.55) | ALDH1A1PTGS2CRHBPCRHR2POLB | |
| SCHEMBL31451911 | 0.84 | ALDH1A1 (0.53) | ALDH1A1GPR35PTGS2POLBRAB9A | |
| Dinitro Cresol SCHEMBL3976321 | 0.83 | GPR35 (0.78) | ALDH1A1GPR35CRHBPCRHR2POLB | |
| SCHEMBL11671011 | 0.82 | CRHBP (0.62) | ALDH1A1GPR35PTGS2CRHBPCRHR2 | |
| SCHEMBL6775236 | 0.81 | PTGS2 (0.54) | ALDH1A1PTGS2CRHBPCRHR2POLB | |
| SCHEMBL1457013 | 0.81 | ALDH1A1 (0.50) | ALDH1A1PTGS2CRHBPCRHR2POLB | |
| SCHEMBL22658133 | 0.81 | MEN1 (0.62) | ALDH1A1PTGS2CRHBPCRHR2POLB | |
| SCHEMBL655655 | 0.78 | GPR35 (0.77) | ALDH1A1GPR35TDP1KMT2AMEN1 | |
| SCHEMBL7137309 | 0.78 | ERN1 (0.52) | PTGS2CRHBPCRHR2POLBRAB9A | |
| SCHEMBL22658164 | 0.78 | MAPT (0.47) | ALDH1A1PTGS2POLBRAB9APTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020230134-A1 | ACSS2 INHIBITORS AND METHODS OF USE THEREOF | METABOMED LTD (IL) | 2020-11-19 | — | — | WO | disclosed |