Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 7/20 | 0.74 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.67 |
| ▸ | DHODH | Q02127 | 1/20 | 0.63 |
| ▸ | IGF2BP2 | Q9Y6M1 | 1/20 | 0.58 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.53 |
| ▸ | MPO | P05164 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 1/20 | 0.53 |
| ▸ | PPARD | Q03181 | 1/20 | 0.53 |
| ▸ | PPARA | Q07869 | 1/20 | 0.53 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.53 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2272713 | 0.91 | ACLY (0.84) | ACLYHDAC2DHODHIGF2BP2HDAC1 | |
| SCHEMBL2274927 | 0.91 | ACLY (0.63) | ACLYHDAC2DHODHIGF2BP2SERPINE1 | |
| SCHEMBL2270222 | 0.90 | DHODH (0.77) | ACLYHDAC2DHODHIGF2BP2SERPINE1 | |
| SCHEMBL2272939 | 0.89 | ACLY (0.71) | ACLYHDAC2DHODHSERPINE1NPC1 | |
| SCHEMBL2276184 | 0.89 | ACLY (0.73) | ACLYHDAC2NPC1RAB9AKMT2A | |
| SCHEMBL2275453 | 0.87 | ACLY (0.76) | ACLYHDAC2DHODHSERPINE1NPC1 | |
| SCHEMBL2274953 | 0.86 | ACLY (0.67) | ACLYHDAC2DHODHIGF2BP2SERPINE1 | |
| SCHEMBL2274023 | 0.86 | ACLY (0.64) | ACLYHDAC2DHODHKMT2AMPO | |
| SCHEMBL21930987 | 0.86 | ACLY (1.00) | ACLYHDAC2SERPINE1 | |
| SCHEMBL2272605 | 0.85 | DHODH (0.73) | ACLYHDAC2DHODHIGF2BP2SERPINE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101094829-B | novel anthranilic acid derivative or salt thereof | TOYAMA CHEMICAL CO.,LTD. (JP) | 2012-02-08 | — | — | CN | disclosed |
| US-7999132-B2 | Anthranilic acid derivative or salt thereof | TOYAMA CHEMICAL CO., LTD. (JP) | 2011-08-16 | — | — | US | disclosed |
| US-20090240052-A1 | NOVEL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF | TOYAMA CHEMICAL CO., LTD. (JP) | 2009-09-24 | — | — | US | disclosed |
| CN-101094829-A | Novel anthranilic acid derivative or salt thereof | TOYAMA CHEMICAL CO LTD (JP) | 2007-12-26 | — | — | CN | disclosed |
| EP-1820795-A1 | NOVEL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF | TOYAMA CHEMICAL CO., LTD. (JP) | 2007-08-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090240052-A1 | NOVEL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF | MMP13, MMP26, MMP11 | ACLY 653/4885HDAC2 276/4885DHODH 1469/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.