Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 5/20 | 0.71 |
| ▸ | PPARG | P37231 | 2/20 | 0.62 |
| ▸ | PPARD | Q03181 | 2/20 | 0.62 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.62 |
| ▸ | PPARA | Q07869 | 1/20 | 0.62 |
| ▸ | KCNK2 | O95069 | 2/20 | 0.58 |
| ▸ | KCNK10 | P57789 | 2/20 | 0.58 |
| ▸ | SERPINE1 | P05121 | 2/20 | 0.56 |
| ▸ | GRIK1 | P39086 | 3/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.54 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | DHODH | Q02127 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2267918 | 0.89 | ACLY (0.74) | ACLYPPARGPPARDNR1H4PPARA | |
| SCHEMBL2272927 | 0.88 | ACLY (0.64) | ACLYKCNK2KCNK10SERPINE1GRIK1 | |
| SCHEMBL2276482 | 0.88 | ACLY (0.74) | ACLYSERPINE1GRIK1HDAC2SUCNR1 | |
| SCHEMBL2277993 | 0.87 | ACLY (0.65) | ACLYKCNK2KCNK10SERPINE1GRIK1 | |
| SCHEMBL2274927 | 0.83 | ACLY (0.63) | ACLYPPARGPPARDNR1H4PPARA | |
| SCHEMBL21930987 | 0.83 | ACLY (1.00) | ACLYSERPINE1HDAC2SUCNR1 | |
| SCHEMBL2269733 | 0.82 | ACLY (0.59) | ACLYKCNK2KCNK10SERPINE1GRIK1 | |
| SCHEMBL2274563 | 0.82 | ACLY (0.81) | ACLYSERPINE1GRIK1SUCNR1KMT2A | |
| SCHEMBL2274998 | 0.81 | ACLY (0.80) | ACLYKCNK2KCNK10SERPINE1GRIK1 | |
| SCHEMBL2276184 | 0.81 | ACLY (0.73) | ACLYHDAC2SUCNR1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101094829-B | novel anthranilic acid derivative or salt thereof | TOYAMA CHEMICAL CO.,LTD. (JP) | 2012-02-08 | — | — | CN | disclosed |
| US-7999132-B2 | Anthranilic acid derivative or salt thereof | TOYAMA CHEMICAL CO., LTD. (JP) | 2011-08-16 | — | — | US | disclosed |
| US-20090240052-A1 | NOVEL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF | TOYAMA CHEMICAL CO., LTD. (JP) | 2009-09-24 | — | — | US | disclosed |
| CN-101094829-A | Novel anthranilic acid derivative or salt thereof | TOYAMA CHEMICAL CO LTD (JP) | 2007-12-26 | — | — | CN | disclosed |
| EP-1820795-A1 | NOVEL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF | TOYAMA CHEMICAL CO., LTD. (JP) | 2007-08-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090240052-A1 | NOVEL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF | MMP13, MMP26, MMP11 | ACLY 653/4885PPARG 2066/4885PPARD 3684/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.