SCHEMBL2268223

SCHEMBL2268223

OC(c1ccc(Br)cc1)c1ccc(Br)cc1

nearest known ligand 0.50

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.50
MAPK1 P28482 2/20 0.46
CFTR P13569 1/20 0.46
ALOX15 P16050 2/20 0.45
CYP1A2 P05177 1/20 0.44
HTR2A P28223 1/20 0.41
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
TSHR P16473 1/20 0.39
CES2 O00748 1/20 0.39
CES1 P23141 1/20 0.39
CYP2C19 P33261 1/20 0.39
ALOX5 P09917 1/20 0.39
CNR1 P21554 1/20 0.39
SLC6A2 P23975 1/20 0.38
SLC6A4 P31645 1/20 0.38
SLC6A3 Q01959 1/20 0.38
ALDH1A1 P00352 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL477648 0.89 HTR2A (0.56) MAPK1HTR2ACA1CA2CNR1
SCHEMBL3858148 0.89 HTR2A (0.56) MAPK1HTR2ACA1CA2CNR1
SCHEMBL5351433 0.87 ALDH1A1 (0.62) CYP2A6MAPK1CFTRCYP1A2CYP2C19
SCHEMBL1980176 0.87 CNR1 (0.47) CYP2A6MAPK1CFTRTSHRCNR1
SCHEMBL5518530 0.87 IGF1R (0.46) CYP2A6MAPK1CFTRCYP1A2
SCHEMBL5512809 0.85 CYP19A1 (0.59) CYP2A6MAPK1CFTRCYP1A2CYP2C19
SCHEMBL11642923 0.83 ALDH1A1 (0.65) MAPK1HTR2ACA1CA2SLC6A2
SCHEMBL23882679 0.82 MAOB (0.53) CYP2A6MAPK1CFTRCA2ALDH1A1
SCHEMBL17159529 0.82 SMN1; SMN2 (0.42) CYP2A6MAPK1CFTRALOX15CYP1A2
SCHEMBL5670372 0.82 MAPK1 (0.55) MAPK1CA1CA2TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112521418-B Sulfhydryl-containing phosphorus-containing flame retardant and preparation method and application thereof 广东广山新材料股份有限公司 2024-04-30 CN claimed
CN-117264211-A Low-melting-point polyarylene sulfide resin and film, and preparation methods and applications thereof 新凝合科技(成都)有限公司 2023-12-22 CN claimed
US-12018004-B2 Carbamate compounds and methods of making and using same H. LUNDBECK A/S (DK) 2024-06-25 US disclosed
CN-112521418-B Sulfhydryl-containing phosphorus-containing flame retardant and preparation method and application thereof 广东广山新材料股份有限公司 2024-04-30 CN disclosed
CN-117264211-A Low-melting-point polyarylene sulfide resin and film, and preparation methods and applications thereof 新凝合科技(成都)有限公司 2023-12-22 CN disclosed
US-20230312499-A1 CARBAMATE COMPOUNDS AND METHODS OF MAKING AND USING SAME H. LUNDBECK A/S (DK) 2023-10-05 US disclosed
US-20230312499-A1 CARBAMATE COMPOUNDS AND METHODS OF MAKING AND USING SAME H. LUNDBECK A/S (DK) 2023-10-05 US disclosed
US-20230312499-A1 CARBAMATE COMPOUNDS AND METHODS OF MAKING AND USING SAME H. LUNDBECK A/S (DK) 2023-10-05 US disclosed
CN-114957692-B Hyperbranched polyphenyl and preparation method and application thereof 苏州大学 2023-08-11 CN disclosed
US-11555013-B2 Potent and selective inhibitors of monoamine transporters; method of making; and use thereof THE USA, AS REPRESENTED BY THE SECRETARY, DHHS (US) 2023-01-17 US disclosed
US-11530189-B2 Carbamate compounds and methods of making and using same H. LUNDBECKA/S (DK) 2022-12-20 US disclosed
US-4987060-A PACKAGED IN SINGLE PART FOR DILUTION WITH WATER MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1991-01-22 US disclosed
EP-0254195-B1 PHOTOGRAPHIC SILVER HALIDE DEVELOPER COMPOSITIONS AND PROCESS FOR FORMING PHOTOGRAPHIC SILVER IMAGES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1990-10-31 EP disclosed
EP-0391154-A2 Concentrated photographic developer composition and method of making it MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1990-10-10 EP disclosed
EP-0329335-A2 Pattern free lithographic elements MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1989-08-23 EP disclosed
US-4777118-A USING A DIARYLCARBINOL MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1988-10-11 US disclosed
US-4756997-A Dihydroxybenzene developer, alpha ketocarboxylic acid stabilizer MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1988-07-12 US disclosed
EP-0254195-A2 Photographic silver halide developer compositions and process for forming photographic silver images MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1988-01-27 EP disclosed
EP-0231850-A2 Process for the formation of high contrast negative images and silver halide photographic element MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1987-08-12 EP disclosed
US-4205087-A ANTIARTHRITIC AGENTS IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1980-05-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11530189-B2 Carbamate compounds and methods of making and using same ABHD6, ABHD16A, RABL6 CYP2A6 218/4885MAPK1 3735/4885CFTR 3861/4885
US-11555013-B2 Potent and selective inhibitors of monoamine transporters; method of making; and use thereof SLC6A2, SLC6A4, SLC6A3 CYP2A6 541/4885MAPK1 3473/4885CFTR 4154/4885
US-20230312499-A1 CARBAMATE COMPOUNDS AND METHODS OF MAKING AND USING SAME ABHD6, ABHD16A, RABL6 CYP2A6 218/4885MAPK1 3735/4885CFTR 3861/4885
US-12018004-B2 Carbamate compounds and methods of making and using same ABHD6, ABHD16A, RABL6 CYP2A6 218/4885MAPK1 3735/4885CFTR 3861/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.