Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2275572 | 0.83 | HRH1 (0.46) | CYP2C19MEN1KMT2ASIGMAR1CYP1A2 | |
| SCHEMBL27614153 | 0.80 | LTA4H (0.33) | SIGMAR1ALDH1A1 | |
| SCHEMBL2271824 | 0.75 | TRPA1 (0.31) | CYP2C19CYP1A2TSHRSLC6A2ALDH1A1 | |
| SCHEMBL2273389 | 0.73 | SIGMAR1 (0.49) | HTTMEN1KMT2ASIGMAR1CYP1A2 | |
| SCHEMBL2275321 | 0.72 | HTR2A (0.46) | HTTSIGMAR1CYP1A2TSHRSLC6A2 | |
| SCHEMBL8344995 | 0.72 | TP53 (0.35) | SIGMAR1TSHRMAOASLC6A2SLC6A4 | |
| SCHEMBL2266973 | 0.71 | CYP2C19 (0.39) | HTTCYP2C19MEN1GLAKMT2A | |
| SCHEMBL2269778 | 0.70 | HTT (0.41) | HTTSIGMAR1ADRB2TSHRSLC6A2 | |
| SCHEMBL2102244 | 0.68 | HTT (0.39) | HTTCYP2C19MEN1GLAKMT2A | |
| SCHEMBL10320035 | 0.66 | TAAR1 (0.37) | SIGMAR1MAOASLC6A2SLC6A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8404584-B2 | Method of manufacturing semiconductor device | FUJITSU LIMITED (JP) | 2013-03-26 | — | — | US | disclosed |
| US-20110207319-A1 | METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE | FUJITSU LIMITED (JP) | 2011-08-25 | — | — | US | disclosed |