Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.53 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 5/20 | 0.42 |
| ▸ | ALDH2 | P05091 | 2/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.37 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.37 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22683259 | 0.95 | BRD4 (0.48) | BRD4PDK2FFAR1MAOBALDH2 | |
| SCHEMBL30185375 | 0.91 | BRD4 (0.52) | BRD4PDK2FFAR1MAOBPDE3B | |
| SCHEMBL22683269 | 0.91 | BRD4 (0.52) | BRD4PDK2FFAR1MAOBPDE3B | |
| SCHEMBL22683260 | 0.86 | ITGB3 (0.43) | PDK2FFAR1MAOBS1PR1 | |
| SCHEMBL22702989 | 0.84 | THRA (0.47) | MAOBMAPTKDM4EEGFR | |
| SCHEMBL20031661 | 0.83 | KDM4E (0.42) | BRD4PDK2MAOBMAPTKDM4E | |
| SCHEMBL20031639 | 0.82 | ALB (0.44) | PDK2MAOBALDH2MAOAS1PR1 | |
| SCHEMBL22683261 | 0.81 | MEN1 (0.46) | MAOBALDH2MAPTLTA4HEGFR | |
| SCHEMBL20031910 | 0.80 | EGFR (0.44) | MAOBMAOAMAPTKDM4EEGFR | |
| SCHEMBL22683275 | 0.79 | ITGB3 (0.38) | PDK2FFAR1MAOBALDH2MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11578040-B2 | [5]Helicene derivatives as molecular reporters for diagnostic applications and methods of synthesis therefor | NATIONAL SCIENCE AND TECHNOLOGY DEVELOPMENT AGENCY (TH) | 2023-02-14 | — | — | US | disclosed |
| US-11578040-B2 | [5]Helicene derivatives as molecular reporters for diagnostic applications and methods of synthesis therefor | NATIONAL SCIENCE AND TECHNOLOGY DEVELOPMENT AGENCY (TH) | 2023-02-14 | — | — | US | disclosed |
| EP-3518746-B1 | [5]HELICENE DERIVATIVES AS MOLECULAR REPORTERS FOR DIAGNOSTIC APPLICATIONS AND METHODS OF SYNTHESIS THEREFOR | NATIONAL SCIENCE AND TECH DEVELOPMENT AGENCY (TH) | 2020-11-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11578040-B2 | [5]Helicene derivatives as molecular reporters for diagnostic applications and methods of synthesis therefor | OR51E2, HDHD5, WEE1 | BRD4 4615/4885PDK2 2438/4885FFAR1 496/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.