SCHEMBL2268378

SCHEMBL2268378

CCCC[SiH](c1ccccc1)N(C)C

nearest known ligand 0.39

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 2/20 0.38
OPRL1 P41146 2/20 0.38
TDP1 Q9NUW8 1/20 0.34
KCNH2 Q12809 4/20 0.33
NPSR1 Q6W5P4 2/20 0.33
SIGMAR1 Q99720 1/20 0.33
PCSK9 Q8NBP7 1/20 0.33
GAA P10253 1/20 0.33
MAPT P10636 1/20 0.33
ALOX12 P18054 1/20 0.33
CRHBP P24387 1/20 0.33
HTT P42858 1/20 0.33
CRHR2 Q13324 1/20 0.33
LTA4H P09960 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
PTGS2 P35354 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2272414 0.88 ALDH1A1 (0.33) TDP1SIGMAR1
SCHEMBL2271138 0.82 LTA4H (0.36) OPRM1OPRL1TDP1KCNH2NPSR1
SCHEMBL2271802 0.79 TSHR (0.41) OPRM1KCNH2SIGMAR1
SCHEMBL114779 0.74 LTA4H (0.38) TDP1SIGMAR1PCSK9LTA4HMEN1
SCHEMBL417994 0.74 LTA4H (0.38) TDP1NPSR1SIGMAR1PCSK9LTA4H
SCHEMBL7815018 0.72 LTA4H (0.36) TDP1NPSR1SIGMAR1PCSK9GAA
SCHEMBL27761182 0.72 AOC3 (0.37) TDP1
SCHEMBL704628 0.71 LTA4H (0.35) TDP1NPSR1SIGMAR1PCSK9GAA
SCHEMBL3482045 0.71 PCSK9 (0.39) NPSR1PCSK9GAAMAPTALOX12
SCHEMBL713125 0.71 LTA4H (0.35) OPRM1OPRL1TDP1SIGMAR1PCSK9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8404584-B2 Method of manufacturing semiconductor device FUJITSU LIMITED (JP) 2013-03-26 US disclosed
US-20110207319-A1 METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2011-08-25 US disclosed