SCHEMBL2268389

SCHEMBL2268389

CCNC(CCC[SiH2]c1ccccc1)NCC

nearest known ligand 0.37

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 2/20 0.37
CNR2 P34972 2/20 0.33
AOC3 Q16853 1/20 0.30
HTR2A P28223 1/20 0.30
HRH1 P35367 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2268970 0.82 HTR2A (0.35) SIGMAR1CNR2HTR2AHRH1
SCHEMBL2099562 0.80 SIGMAR1 (0.42) SIGMAR1
SCHEMBL29404222 0.76 ALDH1A1 (0.37) AOC3HTR2AHRH1
SCHEMBL1274186 0.73 LTA4H (0.38) SIGMAR1
SCHEMBL2269242 0.72 SIGMAR1 (0.35) SIGMAR1HTR2AHRH1
SCHEMBL2268371 0.71 HTR2A (0.35) SIGMAR1AOC3HTR2AHRH1
SCHEMBL3678757 0.71 LTA4H (0.38) SIGMAR1
Fluoride SCHEMBL27639869 0.71 LTA4H (0.36) SIGMAR1
Fluoride SCHEMBL27639867 0.71 LTA4H (0.36) SIGMAR1
SCHEMBL2266537 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8404584-B2 Method of manufacturing semiconductor device FUJITSU LIMITED (JP) 2013-03-26 US disclosed
US-20110207319-A1 METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2011-08-25 US disclosed