SCHEMBL2099562

SCHEMBL2099562

CCNC(C[SiH2]c1ccccc1)NCC

nearest known ligand 0.42

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 4/20 0.42
KCNN4 O15554 1/20 0.33
MTOR P42345 1/20 0.31
RAB9A P51151 1/20 0.31
GRM7 Q14831 1/20 0.31
TP53 P04637 1/20 0.31
PKM P14618 1/20 0.31
LMNA P02545 1/20 0.30
CYP3A4 P08684 1/20 0.30
ALOX15 P16050 1/20 0.30
TSHR P16473 1/20 0.30
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2268389 0.80 SIGMAR1 (0.37) SIGMAR1
SCHEMBL2104457 0.78 TAAR1 (0.39) SIGMAR1PKMCYP3A4ALOX15TSHR
SCHEMBL8427323 0.73 TDP1 (0.37) SIGMAR1CYP3A4ALOX15TSHR
SCHEMBL234049 0.72 SIGMAR1 (0.44) SIGMAR1KCNN4MTORRAB9AGRM7
SCHEMBL8512686 0.72 LMNA (0.35) SIGMAR1RAB9ALMNATSHR
SCHEMBL8727777 0.72 LMNA (0.35) SIGMAR1RAB9ALMNATSHR
SCHEMBL2103828 0.70 TSHR (0.38) MTORRAB9AGRM7CYP3A4ALOX15
SCHEMBL2274476 0.70 KCNN4 (0.35) SIGMAR1KCNN4TP53LMNAHTT
SCHEMBL11012885 0.70 TDP1 (0.34) SIGMAR1LMNACYP3A4TSHR
SCHEMBL23521388 0.69 L3MBTL1 (0.39) TP53PKMHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8404584-B2 Method of manufacturing semiconductor device FUJITSU LIMITED (JP) 2013-03-26 US disclosed
US-8164166-B2 Interfacial roughness reducing film, wiring layer, semiconductor device, and method of manufacturing semiconductor device FUJITSU LIMITED (JP) 2012-04-24 US disclosed
US-20110207319-A1 METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2011-08-25 US disclosed
US-20090085170-A1 INTERFACIAL ROUGHNESS REDUCING FILM, WIRING LAYER, SEMICONDUCTOR DEVICE, AND METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2009-04-02 US disclosed