Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 12/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | DRD1 | P21728 | 1/20 | 0.47 |
| ▸ | FBP1 | P09467 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL6559237 | 0.98 | KIF11 (0.55) | KIF11CA1CA2CYP1A2DRD1 | |
| SCHEMBL61631 | 0.93 | CYP1A2 (0.54) | KIF11CA1CA2CYP1A2FBP1 | |
| Hydrochloric Acid SCHEMBL27615734 | 0.91 | CYP1A2 (0.52) | KIF11CA1CA2CYP1A2FBP1 | |
| SCHEMBL16626288 | 0.86 | CYP1A2 (0.48) | KIF11CA1CA2CYP1A2FBP1 | |
| SCHEMBL13221440 | 0.85 | KIF11 (0.56) | KIF11CA1CA2DRD1 | |
| SCHEMBL28461961 | 0.84 | CYP1A2 (0.47) | KIF11CA1CA2CYP1A2FBP1 | |
| SCHEMBL13989020 | 0.83 | KIF11 (0.49) | KIF11CA1CA2DRD1 | |
| SCHEMBL28753058 | 0.83 | KIF11 (0.49) | KIF11CA1CA2DRD1 | |
| SCHEMBL27932513 | 0.83 | SRD5A2 (0.51) | KIF11CYP1A2FBP1 | |
| SCHEMBL10316101 | 0.82 | COMT (0.44) | KIF11CA1CA2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 262 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113631548-B | Serotonin 5-HT2B inhibiting compounds | 硕腾服务有限责任公司 | 2023-06-06 | — | — | CN | claimed |
| CN-113631548-A | Serotonin 5-HT2B inhibiting compounds | 硕腾服务有限责任公司 | 2021-11-09 | — | — | CN | claimed |
| WO-2015087239-A1 | PROCESSES FOR THE PREPARATION OF DARAPLADIB AND ITS INTERMEDIATES | RANBAXY LABORATORIES LIMITED (IN) | 2015-06-18 | — | — | WO | claimed |
| US-20260078105-A1 | Novel Aminocarboxymuconate Semialdehyde Decarboxylase Inhibitors | ORSOBIO INC (US) | 2026-03-19 | — | — | US | disclosed |
| EP-3450450-B1 | VANCOMYCIN DERIVATIVE, PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND USE THEREOF | SHANGHAI INST MATERIA MEDICA CAS (CN) | 2025-08-27 | — | — | EP | disclosed |
| WO-2024226603-A1 | THERAPEUTIC COMPOUNDS | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2024-10-31 | — | — | WO | disclosed |
| CN-118666841-A | Indole-tetramic acid compound, preparation and medical application thereof | 中国医学科学院药物研究所 | 2024-09-20 | — | — | CN | disclosed |
| CN-116731006-B | Thiazole aminoguanidine compound as well as preparation method and application thereof | 广东省科学院微生物研究所(广东省微生物分析检测中心) | 2024-04-02 | — | — | CN | disclosed |
| CN-116426211-B | Polyamide powder coating for household appliance coating, and preparation method and application thereof | 上海可孚化工有限公司 | 2024-02-13 | — | — | CN | disclosed |
| CN-117430570-A | Rhodamine acetic acid compound, and pharmaceutical composition and application thereof | 中国医学科学院药物研究所 | 2024-01-23 | — | — | CN | disclosed |
| US-20230302162-A1 | RADIOLABELED DARAPLADIB AND ANALOGS THEREOF AND THEIR USE AS IMAGING COMPOUNDS | INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) (FR) | 2023-09-28 | — | — | US | disclosed |
| US-20020173665-A1 | Trisubstituted-N-[(1S)-1,2,3,4-tetrahydro-1-naphthalenyl] benzamides which inhibit P2X3 and P2X2/3 containing receptors | ABBOTT LABORATORIES | 2002-11-21 | — | — | US | disclosed |
| WO-2002030904-A1 | PYRIDINONE DERIVATIVES FOR TREATMENT OF ATHEROSCLEROSIS | SMITHKLINE BEECHAM P.L.C. (GB) | 2002-04-18 | — | — | WO | disclosed |
| WO-2002030911-A1 | PYRIMIDINONE DERIVATIVES AND THEIR USE IN THE TREATMENT OF ATHEROSCLEROSIS | SMITHKLINE BEECHAM P.L.C. (GB) | 2002-04-18 | — | — | WO | disclosed |
| EP-1122234-A9 | Production methods of alpha, alpha, alpha-trifluoromethylphenyl-substituted benzoic acid and intermediate therefor | SUMIKA FINE CHEMICALS Co., Ltd. (JP) | 2002-01-16 | — | — | EP | disclosed |
| US-20010020110-A1 | Production methods of alpha, alpha, alpha-trifluoromethylphenyl-substituted benzoic acid and intermediate therefor | SUMIKA FINE CHEMICALS CO., LTD. (JP) | 2001-09-06 | — | — | US | disclosed |
| EP-1122234-A2 | Production methods of alpha, alpha, alpha-trifluoromethylphenyl-substituted benzoic acid and intermediate therefor | SUMIKA FINE CHEMICALS Co., Ltd. (JP) | 2001-08-08 | — | — | EP | disclosed |
| EP-0098629-B1 | ANTI-COAGULANTS OF THE 4-HYDROXYCOUMARIN TYPE, THE PREPARATION THEREOF, AND RODENTICIDAL COMPOSITIONS (BAITS) COMPRISING SUCH ANTI-COAGULANTS | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1987-08-26 | — | — | EP | disclosed |
| US-4520007-A | Anti-coagulants of the 4-hydroxycoumarin type and rodenticidal compositions (baits) comprising such anti-coagulants | SHELL OIL COMPANY (US) | 1985-05-28 | — | — | US | disclosed |
| EP-0098629-A1 | Anti-coagulants of the 4-hydroxycoumarin type, the preparation thereof, and rodenticidal compositions (baits) comprising such anti-coagulants | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1984-01-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020173665-A1 | Trisubstituted-N-[(1S)-1,2,3,4-tetrahydro-1-naphthalenyl] benzamides which inhibit P2X3 and P2X2/3 containing receptors | P2RX3, P2RX1, P2RX2 | KIF11 4374/4885CA1 2980/4885CA2 576/4885 |
| US-20260078105-A1 | Novel Aminocarboxymuconate Semialdehyde Decarboxylase Inhibitors | CPT1B, CBR1, MUSK | KIF11 4651/4885CA1 1765/4885CA2 721/4885 |
| US-20010020110-A1 | Production methods of alpha, alpha, alpha-trifluoromethylphenyl-substituted benzoic acid and intermediate therefor | SLC6A11, CYP4F11, SLC39A11 | KIF11 1001/4885CA1 404/4885CA2 151/4885 |
| US-20230302162-A1 | RADIOLABELED DARAPLADIB AND ANALOGS THEREOF AND THEIR USE AS IMAGING COMPOUNDS | PLA2G4B, PLA2G1B, PLA2G12B | KIF11 4787/4885CA1 3545/4885CA2 4304/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.