Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR91 | A4D1P6 | 3/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.38 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.36 |
| ▸ | PDE2A | O00408 | 2/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.36 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.36 |
| ▸ | NNMT | P40261 | 1/20 | 0.35 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.35 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22685248 | 0.92 | PTPN1 (0.39) | PTPN1PDE2ANNMTMKNK1MKNK2 | |
| SCHEMBL22685191 | 0.85 | WDR91 (0.43) | WDR91PDE2AABL1IDO1KCNH2 | |
| SCHEMBL22685351 | 0.84 | WDR91 (0.54) | WDR91PDE2AIDO1 | |
| SCHEMBL22684822 | 0.81 | WDR91 (0.40) | WDR91PDE2AABL1IDO1KCNH2 | |
| SCHEMBL22685250 | 0.79 | PTPN1 (0.40) | PTPN1PDE2AABL1NNMTMKNK1 | |
| SCHEMBL22685075 | 0.78 | IDO1 (0.43) | WDR91PTPN1PDE2AABL1SCN9A | |
| SCHEMBL22684799 | 0.76 | IDO1 (0.39) | PDE2AABL1IDO1KCNH2HDAC3 | |
| SCHEMBL22685074 | 0.74 | IDO1 (0.51) | WDR91PDE2AABL1IDO1KCNH2 | |
| SCHEMBL22685173 | 0.73 | IDO1 (0.42) | WDR91PDE2AIDO1 | |
| SCHEMBL22685330 | 0.73 | CXCR3 (0.42) | PDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020228823-A1 | NOVEL AMIDE COMPOUNDS AND USES THEREOF | HUTCHISON MEDIPHARMA LIMITED (CN) | 2020-11-19 | — | — | WO | disclosed |