Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 1/20 | 0.41 |
| ▸ | WDR91 | A4D1P6 | 3/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 4/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.39 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | AKT1 | P31749 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | CXCR3 | P49682 | 2/20 | 0.36 |
| ▸ | PDE2A | O00408 | 3/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22686788 | 0.84 | HDAC3 (0.46) | BTKWDR91MAP4K4HDAC3HDAC1 | |
| SCHEMBL22686789 | 0.83 | WDR91 (0.43) | BTKWDR91MAP4K4HDAC3HDAC1 | |
| SCHEMBL22685171 | 0.80 | WDR91 (0.43) | WDR91PTGER4PTGDRHDAC3HDAC1 | |
| SCHEMBL22686791 | 0.79 | WDR91 (0.44) | BTKWDR91MAP4K4HDAC3HDAC1 | |
| SCHEMBL22685324 | 0.78 | WDR91 (0.40) | WDR91PTGER4PTGDRHDAC3HDAC1 | |
| SCHEMBL22685198 | 0.77 | WDR91 (0.53) | WDR91MAP4K4HDAC3HDAC1HDAC2 | |
| SCHEMBL22685173 | 0.77 | IDO1 (0.42) | WDR91MAP4K4PTGER4PTGDRIDO1 | |
| SCHEMBL22685236 | 0.77 | HDAC3 (0.46) | BTKMAP4K4HDAC3HDAC1HDAC2 | |
| SCHEMBL22686783 | 0.77 | WDR91 (0.42) | BTKWDR91MAP4K4HDAC3HDAC1 | |
| SCHEMBL22685238 | 0.75 | HDAC3 (0.47) | BTKWDR91HDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020228823-A1 | NOVEL AMIDE COMPOUNDS AND USES THEREOF | HUTCHISON MEDIPHARMA LIMITED (CN) | 2020-11-19 | — | — | WO | disclosed |