Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 2/20 | 0.34 |
| ▸ | BACE1 | P56817 | 3/20 | 0.33 |
| ▸ | BACE2 | Q9Y5Z0 | 3/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | KCNQ3 | O43525 | 2/20 | 0.31 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.31 |
| ▸ | KCNE1 | P15382 | 2/20 | 0.31 |
| ▸ | KCNQ1 | P51787 | 2/20 | 0.31 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.31 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | AKT1 | P31749 | 1/20 | 0.31 |
| ▸ | MET | P08581 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22686795 | 0.72 | BTK (0.38) | ABL1HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL22685252 | 0.72 | PDE2A (0.32) | ABL1KCNQ3KCNQ2KCNE1KCNQ1 | |
| SCHEMBL22686788 | 0.68 | HDAC3 (0.46) | ABL1HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL22685236 | 0.68 | HDAC3 (0.46) | HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL22685237 | 0.65 | BTK (0.41) | ABL1HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL22685196 | 0.65 | WDR91 (0.42) | ABL1 | |
| SCHEMBL22686789 | 0.65 | WDR91 (0.43) | HDAC3HDAC1HDAC2HDAC6AKT1 | |
| SCHEMBL22686791 | 0.62 | WDR91 (0.44) | ABL1HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL13666220 | 0.62 | SLC6A4 (0.35) | MAOBKCNQ3KCNQ2KCNE1KCNQ1 | |
| SCHEMBL24968703 | 0.58 | HDAC6 (0.54) | HDAC3HDAC1HDAC2HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020228823-A1 | NOVEL AMIDE COMPOUNDS AND USES THEREOF | HUTCHISON MEDIPHARMA LIMITED (CN) | 2020-11-19 | — | — | WO | disclosed |