Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 8/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.32 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.32 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.32 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.32 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.31 |
| ▸ | ABL1 | P00519 | 3/20 | 0.30 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.30 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.30 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.30 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.30 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.30 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22685253 | 0.78 | PDE2A (0.42) | PDE2AIDO1HDAC3HDAC1HDAC2 | |
| SCHEMBL22685256 | 0.72 | DHFR (0.34) | HDAC3HDAC1HDAC2HDAC6ABL1 | |
| SCHEMBL22685235 | 0.70 | CLK1 (0.35) | IDO1 | |
| SCHEMBL22684801 | 0.67 | PDE2A (0.38) | PDE2AHDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL22685312 | 0.66 | BTK (0.38) | PDE2AIDO1HDAC3HDAC1HDAC2 | |
| SCHEMBL22685238 | 0.63 | HDAC3 (0.47) | HDAC3HDAC1HDAC2HDAC6CYP3A4 | |
| SCHEMBL23908259 | 0.60 | IDO1 (0.45) | PDE2AIDO1 | |
| SCHEMBL23919028 | 0.60 | IDO1 (0.60) | PDE2AIDO1HDAC3HDAC1HDAC2 | |
| SCHEMBL23908253 | 0.59 | IDO1 (0.45) | PDE2AIDO1HDAC3HDAC1HDAC2 | |
| SCHEMBL23908255 | 0.59 | IDO1 (0.45) | PDE2AIDO1HDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020228823-A1 | NOVEL AMIDE COMPOUNDS AND USES THEREOF | HUTCHISON MEDIPHARMA LIMITED (CN) | 2020-11-19 | — | — | WO | disclosed |