Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.34 |
| ▸ | AKT1 | P31749 | 1/20 | 0.34 |
| ▸ | AKT2 | P31751 | 1/20 | 0.34 |
| ▸ | PDE2A | O00408 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24394081 | 0.74 | SLC6A3 (0.49) | MEN1KMT2AHSD11B1PDE2ASLC6A3 | |
| SCHEMBL29502570 | 0.71 | AGBL2 (0.43) | RAB9AKDM4ESMN1; SMN2ALDH1A1TRPM8 | |
| SCHEMBL13197431 | 0.71 | SLC6A3 (0.51) | HSD11B1SLC6A3 | |
| SCHEMBL26375520 | 0.71 | ALDH1A1 (0.44) | RAB9AKDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL9751737 | 0.69 | SLC6A3 (0.56) | MEN1KMT2ASLC6A3 | |
| SCHEMBL22685372 | 0.69 | KDM4E (0.40) | KDM4ESMN1; SMN2ALDH1A1POLBAKT1 | |
| SCHEMBL1765224 | 0.68 | KIF11 (0.47) | KDM4EALDH1A1TRPV1 | |
| SCHEMBL1765772 | 0.68 | KIF11 (0.47) | KDM4ESMN1; SMN2ALDH1A1PTGS1POLB | |
| Ammonia Solution, Strong SCHEMBL28005559 | 0.68 | SLC6A3 (0.54) | MEN1KMT2ASLC6A3 | |
| SCHEMBL13838853 | 0.67 | OPRL1 (0.52) | HSD11B1ALDH1A1SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020228823-A1 | NOVEL AMIDE COMPOUNDS AND USES THEREOF | HUTCHISON MEDIPHARMA LIMITED (CN) | 2020-11-19 | — | — | WO | disclosed |