Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPB1 | P04792 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 7/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | MEN1 | O00255 | 6/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | ERO1A | Q96HE7 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5962918 | 0.78 | NOTUM (0.55) | HTTALDH1A1SMN1; SMN2L3MBTL1MAPT | |
| SCHEMBL15911431 | 0.76 | HSPB1 (0.71) | HSPB1LMNAHTTALDH1A1MEN1 | |
| SCHEMBL31413300 | 0.74 | ALDH1A1 (0.41) | LMNAHTTALDH1A1MEN1KMT2A | |
| SCHEMBL23702646 | 0.74 | ALDH1A1 (0.41) | LMNAHTTALDH1A1MEN1KMT2A | |
| SCHEMBL30104052 | 0.74 | ALDH1A1 (0.41) | LMNAHTTALDH1A1MEN1KMT2A | |
| SCHEMBL23712697 | 0.74 | TSHR (0.50) | LMNAHTTALDH1A1MEN1KMT2A | |
| SCHEMBL23702657 | 0.74 | ALDH1A1 (0.41) | LMNAHTTALDH1A1MEN1KMT2A | |
| SCHEMBL2643542 | 0.74 | KEAP1 (0.52) | LMNAALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL15911443 | 0.73 | HSPB1 (0.65) | HSPB1LMNAHTTALDH1A1MEN1 | |
| SCHEMBL22686984 | 0.73 | HSPB1 (0.65) | HSPB1LMNAHTTALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200369626-A1 | COMPOSITIONS OF SPHINGOSINE-1-PHOSPHATE RECEPTOR 2 (S1PR2) BINDING AGENTS AND USES THEREOF | WASHINGTON UNIVERSITY (US) | 2020-11-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200369626-A1 | COMPOSITIONS OF SPHINGOSINE-1-PHOSPHATE RECEPTOR 2 (S1PR2) BINDING AGENTS AND USES THEREOF | S1PR2, S1PR1, S1PR3 | HSPB1 3013/4885LMNA 1789/4885HTT 2910/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.