SCHEMBL2268949

SCHEMBL2268949

CCN[SiH2]c1ccccc1C(C)(C)C

nearest known ligand 0.38

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.38
ALDH1A1 P00352 2/20 0.38
TDP1 Q9NUW8 1/20 0.38
CA2 P00918 1/20 0.34
MAPT P10636 1/20 0.33
GAA P10253 2/20 0.32
POLB P06746 1/20 0.32
THRB P10828 1/20 0.32
ALOX12 P18054 1/20 0.32
KCNN4 O15554 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31
GABRA1 P14867 1/20 0.31
GABRB2 P47870 1/20 0.31
KDM4E B2RXH2 1/20 0.30
KMT2A Q03164 1/20 0.30
KIF11 P52732 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2103819 0.86 ALDH1A1 (0.33) TSHRALDH1A1TDP1CA2MAPT
SCHEMBL2103512 0.81 CACNA2D1 (0.33) TSHRALDH1A1TDP1GAAKDM4E
SCHEMBL2272999 0.78 ALDH1A1 (0.41) TSHRALDH1A1TDP1CA2MAPT
SCHEMBL27173776 0.73 ALDH1A1 (0.44) TSHRALDH1A1TDP1CA2MAPT
SCHEMBL2269758 0.71 TSHR (0.39) TSHRALDH1A1TDP1CA2CYP1A2
SCHEMBL27660681 0.69 ALDH1A1 (0.38) TSHRALDH1A1TDP1CA2GAA
SCHEMBL15655352 0.69 ALDH1A1 (0.50) TSHRALDH1A1TDP1CA2MAPT
SCHEMBL2272712 0.69 TDP1 (0.44) TSHRALDH1A1TDP1CA2GABRA1
SCHEMBL9504489 0.69 ALDH1A1 (0.44) TSHRALDH1A1TDP1CA2MAPT
SCHEMBL19921960 0.67 ALDH1A1 (0.43) TSHRALDH1A1TDP1CA2GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8404584-B2 Method of manufacturing semiconductor device FUJITSU LIMITED (JP) 2013-03-26 US disclosed
US-20110207319-A1 METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2011-08-25 US disclosed