SCHEMBL22689650

SCHEMBL22689650

Cc1ccc(S(=O)(=O)n2cc(Br)cc2C=C[N+](=O)[O-])cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FBP1 P09467 2/20 0.44
CA2 P00918 3/20 0.41
CA1 P00915 2/20 0.41
KDM4E B2RXH2 1/20 0.38
UBE2N P61088 1/20 0.38
PKM P14618 1/20 0.37
RAPGEF4 Q8WZA2 1/20 0.35
L3MBTL1 Q9Y468 3/20 0.35
MAOA P21397 1/20 0.34
MAOB P27338 1/20 0.34
HTR2A P28223 1/20 0.34
HTR2C P28335 1/20 0.34
HTR6 P50406 1/20 0.34
GAA P10253 1/20 0.34
TSHR P16473 1/20 0.34
CYP2C19 P33261 1/20 0.34
POLB P06746 1/20 0.34
ALDH3A1 P30838 1/20 0.34
HTT P42858 1/20 0.34
NOD1 Q9Y239 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22689649 1.00 FBP1 (0.44) FBP1CA2CA1KDM4EUBE2N
SCHEMBL28736851 0.81 RAPGEF4 (0.38) FBP1KDM4ERAPGEF4L3MBTL1HTR6
SCHEMBL4170909 0.81 KDM4E (0.49) CA2CA1KDM4EUBE2NPKM
SCHEMBL29564645 0.81 CA1 (0.42) CA2CA1KDM4EUBE2NPKM
SCHEMBL4312459 0.77 RAPGEF4 (0.50) FBP1CA2CA1KDM4EUBE2N
SCHEMBL4312461 0.77 RAPGEF4 (0.50) FBP1CA2CA1KDM4EUBE2N
SCHEMBL29493318 0.72 MAPT (0.41) FBP1MAOAMAOBGAATSHR
SCHEMBL3464148 0.72 ALDH1A1 (0.40) CA2CA1KDM4EUBE2NRAPGEF4
SCHEMBL18951969 0.72 CA1 (0.49) CA2CA1KDM4EUBE2NPKM
SCHEMBL28904396 0.72 CA1 (0.49) CA2CA1KDM4EUBE2NPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119752217-A Narrow emission dyes, compositions comprising the same, and methods of making and using the same 尼尔瓦纳科学股份有限公司 2025-04-04 CN disclosed
CN-114222803-B Narrow emission dyes, compositions comprising the same, and methods of making and using the same 尼尔瓦纳科学股份有限公司 2025-01-07 CN disclosed
EP-3959293-B1 NARROW EMISSION DYES, COMPOSITIONS COMPRISING SAME, AND METHODS FOR MAKING AND USING SAME NIRVANA SCIENCES INC (US) 2024-11-13 EP disclosed
US-20220249707-A1 NARROW EMISSION DYES, COMPOSITIONS COMPRISING SAME, AND METHODS FOR MAKING AND USING SAME NIRVANA SCIENCES INC. (US) 2022-08-11 US disclosed
EP-3959293-A1 NARROW EMISSION DYES, COMPOSITIONS COMPRISING SAME, AND METHODS FOR MAKING AND USING SAME NIRvana Sciences Inc. (US) 2022-03-02 EP disclosed
WO-2020236818-A1 NARROW EMISSION DYES, COMPOSITIONS COMPRISING SAME, AND METHODS FOR MAKING AND USING SAME NIRVANA SCIENCES INC. (US) 2020-11-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220249707-A1 NARROW EMISSION DYES, COMPOSITIONS COMPRISING SAME, AND METHODS FOR MAKING AND USING SAME AQP4, CLSPN, CHLSN FBP1 4526/4885CA2 835/4885CA1 165/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.